<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13042

Description U-box domain-containing protein 35-like isoform X1
SequenceMEKKEREEAENELVLPPSPTLTIGIAINGNRESKYVVKWALEKFVPEGNVMFKLLHVRAKIKLIPTPMGNLLPISQVREDVAAAYKKELEWQANEMLLPYKKMCAQRKVEADIIIIESDQVANAIAEEVSKNTITRLVIGASSRGMFTRKLKKNNLSSRISACAPSFCTVYAVSKGKLTSIRPSDSEMNGSTKDDSSETSFSSKNSSDYSFSSQTELGSVATYATFRSPSLPMQRSQALSTINQTHLHSRTSSLSRSTESTQFKSPDNNHSRCQSLDNAAGNDDMSSCPNSSESREAVSQNSSHRSLQTDQQSWLPDQISTLDAQTDNNPSECQVNINFEIEKLRTELRHIREMHAAAQSETIDASQKLNTLSKRRLEEAMKLKEVCLKEEEAKELARQEKAKCEAAIREAVHVKGRADREASLRQEAEMKASHEAKEKEKLQNYLTGPLQQYQKFTWDEIVSATSSFSEDLRIGMGAYGTVYKCIFHHTAAAVKVLHSKENGRTKQFQQELEILSKIRHPHLLLLLGACPEHGCLVYEYMENGSLEDRLLRKNNTPPIPWFERYRIAWEVGSALVFLHNSKPEPIIHRDLKPANILLDHNFMSKIGDVGLSMMITTDSSSTSTVYKDTGPVGTLCYIDPEYQRTGLISPKSDIYAFGMIILQLLTAKPAIALTHVVETAIDDDNLTRILDSEAGNWPVEETKELAILGLSCAELRRKDRPGLKDRVLPILEKMKEVANKARNSISNIQSAHPSHFICPISKDVMDEPCVAADGYTYERKAIEKWIETNDISPMTNLALPNKNLLPNYSLLSAILEWKSRKQ
Length822
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.507
Instability index48.93
Isoelectric point6.75
Molecular weight92249.80
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13042
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.07|      14|      82|       3|      16|       1
---------------------------------------------------------------------------
    3-   16 (24.26/16.80)	KKEREEAENELVLP
   86-   99 (26.81/19.38)	KKELEWQANEMLLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.74|      20|      20|     248|     267|       2
---------------------------------------------------------------------------
  248-  267 (34.73/25.45)	HSRTSSLSRSTESTQFKS.PD
  270-  290 (33.01/23.78)	HSRCQSLDNAAGNDDMSScPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.66|      24|      83|     403|     434|       3
---------------------------------------------------------------------------
  376-  400 (34.23/13.44)	RLEEAMKlKEVCLKEEEAKELA.RQE
  403-  427 (35.43/32.73)	KCEAAIR.EAVHVKGRADREASlRQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.16|      15|      18|      43|      58|       5
---------------------------------------------------------------------------
   43-   58 (23.55/20.40)	KFVPE..GNvMFKLLHVR
   62-   78 (21.61/13.06)	KLIPTpmGN.LLPISQVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     226.28|      49|     454|     147|     195|       6
---------------------------------------------------------------------------
  147-  195 (82.47/55.80)	FTRKLKKNNLSSRISACAPSFCTVY..AVSKGKLTSIRPSDSEMNG..STKDD
  479-  507 (25.04/11.75)	....................YGTVY.kCIFHHTAAAVKVLHSKENG..RTKQ.
  517-  548 (46.69/28.36)	...KIRHPHLLLLLGACPEHGCLVY...............EYMENG..SLED.
  602-  653 (72.08/47.83)	FMSKIGDVGLSMMITTDSSSTSTVYkdTGPVGTLCYIDP.EYQRTGliSPKSD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13042 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TYATFRSPSLPMQRSQALSTINQTHLHSRTSSLSRSTESTQFKSPDNNHSRCQSLDNAAGNDDMSSCPNSSESREAVSQNSSHRSLQTDQQSWLPDQISTLDAQTDNNPSECQVNINF
222
339










Molecular Recognition Features






MoRF SequenceStartStop




NANANA