<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13041

Description U-box domain-containing protein 35-like isoform X2
SequenceMFTRKLKKNNLSSRISACAPSFCTVYAVSKGKLTSIRPSDSEMNGSTKDDSSETSFSSKNSSDYSFSSQTELGSVATYATFRSPSLPMQRSQALSTINQTHLHSRTSSLSRSTESTQFKSPDNNHSRCQSLDNAAGNDDMSSCPNSSESREAVSQNSSHRSLQTDQQSWLPDQISTLDAQTDNNPSECQVNINFEIEKLRTELRHIREMHAAAQSETIDASQKLNTLSKRRLEEAMKLKEVCLKEEEAKELARQEKAKCEAAIREAVHVKGRADREASLRQEAEMKASHEAKEKEKLQNYLTGPLQQYQKFTWDEIVSATSSFSEDLRIGMGAYGTVYKCIFHHTAAAVKVLHSKENGRTKQFQQELEILSKIRHPHLLLLLGACPEHGCLVYEYMENGSLEDRLLRKNNTPPIPWFERYRIAWEVGSALVFLHNSKPEPIIHRDLKPANILLDHNFMSKIGDVGLSMMITTDSSSTSTVYKDTGPVGTLCYIDPEYQRTGLISPKSDIYAFGMIILQLLTAKPAIALTHVVETAIDDDNLTRILDSEAGNWPVEETKELAILGLSCAELRRKDRPGLKDRVLPILEKMKEVANKARNSISNIQSAHPSHFICPISKDVMDEPCVAADGYTYERKAIEKWIETNDISPMTNLALPNKNLLPNYSLLSAILEWKSRKQ
Length677
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.571
Instability index53.79
Isoelectric point6.60
Molecular weight75982.95
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13041
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.66|      24|      26|     231|     255|       1
---------------------------------------------------------------------------
  231-  255 (34.23/35.19)	RLEEAMKlKEVCLKEEEAKELA.RQE
  258-  282 (35.43/30.04)	KCEAAIR.EAVHVKGRADREASlRQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     205.46|      49|     454|       2|      50|       2
---------------------------------------------------------------------------
    2-   50 (82.04/51.34)	FTRKLKKNNLSSRISACAPSFCTVY.A.VSK..GKLTSIRPSDSEMNG..STKDD
  334-  362 (24.18/10.08)	....................YGTVYkC.IFH..HTAAAVKVLHSKENG..RTKQ.
  372-  401 (28.33/13.04)	...KIRHPHLLLLLGACPEHGCLVY.EyMEN..GSL...................
  457-  508 (70.92/43.41)	FMSKIGDVGLSMMITTDSSSTSTVY.K.DTGpvGTLCYIDP.EYQRTGliSPKSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     146.33|      46|      57|      76|     129|       3
---------------------------------------------------------------------------
   76-  129 (74.57/64.91)	ATYATFRS.PSLPMQR........SQALSTINQTHLHSRTSSLSRSTestqfkspDNNHSRCQ
  135-  189 (71.77/47.05)	AGNDDMSScPNSSESReavsqnssHRSLQTDQQSWLPDQISTLDAQT........DNNPSECQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13041 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TYATFRSPSLPMQRSQALSTINQTHLHSRTSSLSRSTESTQFKSPDNNHSRCQSLDNAAGNDDMSSCPNSSESREAVSQNSSHRSLQTDQQSWLPDQISTLDAQTDNNPSECQVNINF
77
194










Molecular Recognition Features






MoRF SequenceStartStop




NANANA