<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13038

Description U-box domain-containing protein 33 isoform X1
SequenceMALVSVVPAITEGVNSMRFCDVRAPGIMSSRREIVEETVARIIEEKIYVAVGKDVDKYKSVLFWALQHSGGKKICIIHVHQPAKMIPVSEMGTKFPASKLEEQQVKAYWEIERKNMEKMLNDYLLLCLQRGVRAEKLYIEMDSIEQGILEMISENRIRMLVMGGAADKHYSKYKPHKKVVDLKSKKAIFVRENAPNTCHTIWFLCKGLLIYTRKLSSDVTDTKVASSSLPASPNLESSENHFRSQCVILRQTSQVKPSTSAPDSLHRVRSENVYGRMGSTLGFPSPDGNEGLSTPPNRSDVEGSSDEWDGLSRRSPQNSVLSSCSSNGMADAALVPYMGTEVNGNGLQSSLISHAEGNFNLSSLPSIRDVTTDNTLYDQLQQVMAEETNSRREAFEEAMKRSEAEKDALVAIRRVKASEILYAQELKQRKEIEEALAKEKDELDKMMNQRDEVRIEVQAALDQKSLLENQIAESEKEVKELQEKIFSAVELLQNYKKERDELQMERDNALKEAEELRKSRAEPSGAHMHQFFTEFSFTEIEEATLNFDPSLKIGEGGYGSIYKGNLRHTTVAIKMLHSNSLQGPSEFQQEVDVLSKMRHPNLVTLIGACPDAWTLIYEYLPNGSLEDRLSCRGNSPPLSWQTRIRLATELCSVLIFLHSSKPHGIVHGDLKPANILLDANFVTKLSDFGICRLVSNNTTVCCRTDPKGTFAYMDPEFLSTGELTQKADVYSFGVILLRLLTGRQALGIIKEVQYALDNGNLKNLLDPLAGDWPFVQAEQLANLALRCCEMNRRCRPDLSTDVWRVLEPMRASCGGSSSFQLGSEEQCHPPSYFICPIFQEVMQDPHVAADGFTYEAEALRGWLDSGHHTSPMTNIKLAHSNLVPNLALRSAIQEWLQQH
Length899
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.392
Instability index50.72
Isoelectric point5.84
Molecular weight100931.81
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13038
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     144.09|      55|      65|     378|     442|       1
---------------------------------------------------------------------------
  378-  435 (82.38/64.19)	DQ..LQQVMAEETNSRRE....AFE..EAMKRSEAEKDALVAIRRVKASEilyAQELKQRK..................EIEEA
  463-  543 (61.71/30.48)	QKslLENQIAESEKEVKElqekIFSavELLQNYKKERDELQMERDNALKE...AEELRKSRaepsgahmhqfftefsftEIEEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.88|      18|      26|     257|     275|       2
---------------------------------------------------------------------------
  257-  275 (28.61/22.42)	PSTSAPDSLHR..VRSeNVYG
  284-  303 (28.27/16.92)	PSPDGNEGLSTppNRS.DVEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.40|      18|     344|     319|     336|       5
---------------------------------------------------------------------------
  312-  329 (29.87/15.83)	SRRSPQNSVLSSCSSNGM
  330-  347 (29.53/15.58)	ADAALVPYMGTEVNGNGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.64|      37|     108|      22|      60|       8
---------------------------------------------------------------------------
   22-   59 (57.81/48.49)	VRAPGIMSSRREIvEETVARII.EEKIYVAV.GKDVDK....YK
  132-  174 (48.83/30.58)	VRAEKLYIEMDSI.EQGILEMIsENRIRMLVmGGAADKhyskYK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.67|      20|     299|     443|     462|       9
---------------------------------------------------------------------------
  443-  462 (34.85/25.47)	LDKMMNQRDEVRI..EVQAALD
  736-  757 (28.82/19.77)	LLRLLTGRQALGIikEVQYALD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13038 with Med32 domain of Kingdom Viridiplantae
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