<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13033

Description luminal-binding protein 5-like
SequenceMARSWRASGSLVVLAIVLSGCFFAIAIAKEEAAKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDSERLIGEAAKNQAAVNAERTIFDVKRLIGRKFEDKEVQRDMKLVPYKIVNKDGKPYIQVKIKDGETKVFSPEEISAMVLTKMKETAEAFLGKKIKDAVVTVPAYFNDAQRQATKDAGIIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDQRIMEYFIKLIKKKHGKDISKDNRALGKLRREAERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMGPVKKAMEDAGLQKSQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGKFDLTGIPPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNDKGRLSQEEIERMVREAEEFAEEDKKVKERIDGRNSLETYIYNMKNQINDKDKLADKLESDEKEKVETAVKEALEWLDDNQSAEKEDYEEKLKEVEAVCNPIITAVYQRSGGAPGGGSTEEDDDSHDEL
Length666
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.440
Instability index29.05
Isoelectric point5.13
Molecular weight73380.29
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13033
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.61|      25|      27|     563|     587|       1
---------------------------------------------------------------------------
  563-  587 (40.61/23.07)	KVKERI..DGRNSLETYIYNMKNQIND
  590-  616 (32.14/16.94)	KLADKLesDEKEKVETAVKEALEWLDD
  628-  645 (21.86/ 9.50)	KLKEVE..AVCNPIITAVYQ.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.06|      14|      31|     101|     114|       2
---------------------------------------------------------------------------
   78-   91 (20.95/10.54)	DSERLIGEAAKNQA
  101-  114 (23.49/12.65)	DVKRLIGRKFEDKE
  130-  143 (23.62/12.76)	DGKPYIQVKIKDGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.30|      11|      31|     232|     242|       3
---------------------------------------------------------------------------
  232-  242 (20.46/11.73)	LGGGTFDVSIL
  260-  270 (21.85/13.02)	LGGEDFDQRIM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     210.12|      56|     195|     161|     231|       4
---------------------------------------------------------------------------
  161-  217 (86.23/43.27)	KETAEAFLGKK......IKDAVVTVPA.............YFNDAQRQATKDAGIIAGLNVARIINEPTaAAIAYG
  351-  404 (58.92/23.29)	KAMEDAGLQKS......QIDEIVLVGGstripkvqqllkdYFDG..KEPNK..G..........VN.PD.EAVAYG
  446-  500 (64.98/37.71)	IPRNTVIPTKKsqvfttYQDQQTTVSI.............QVFEGERSLTKDCRLLGKFDLTGIPPAP........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.00|      17|      27|     501|     518|       5
---------------------------------------------------------------------------
  501-  518 (26.00/21.03)	RGTPQIE.VTFEVDaNGIL
  525-  542 (25.00/14.84)	KGTGKSEkITITND.KGRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.03|      14|     193|     218|     231|       6
---------------------------------------------------------------------------
  218-  231 (25.12/15.09)	LDKKGGE..KNILVFD
  412-  427 (19.91/10.33)	LSGEGGDetKDILLLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.79|      18|      27|      13|      30|       7
---------------------------------------------------------------------------
   13-   30 (28.55/23.70)	VLAIVLSGCFFAIAIAKE
   38-   55 (31.24/26.72)	VIGIDLGTTYSCVGVYKN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13033 with Med37 domain of Kingdom Viridiplantae
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