<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13025

Description pre-mRNA-processing protein 40A-like
SequenceMDPSQNFPPPMTGQFRPVVPSQQPQQFVSVPPQQFQPVGRGVTVMNAGFPSQTPQPQFPQVMQQLPARPGHILPPPPSASLPAAQPNQHVNPGASVPQPNIQAPNNYFPGVPASHLSSSYTFAPSSYGQVTVSHNAMAQYQPMAQLQAPNVPVGGQVGIHVSQSTSVTSAQQIGEHPSASTATIPPKPTEEALTDWIEHTSANGRRYYYNRKTRQSSWEKPLELMTPIERADASTNWKEYTSPDGRKYYYNKVTNLSTWSLPEELKLAREQVEMASAKGPQSEVSSHFPAPVPPASKAQSGADTSSTIIQGASSSPVPVAPVPSTSKIESVVVSGSDLPVATSSTVTNVDVVQIVEDTVTPSVAVSESSEVSLSVADAATTPMNNISKVSSLDMVSSEGVSTQNADETVKDVVVSEKINNALEEKAIDQESLTYASKQEAKDAFKALLESANVGSDWTWDQAMRVIINDKRYGALRTLGERKQAFNEFLGQKKKQDAEERRIKQKKAREEYKKMLEECLELTSSTRWSKAVTMFEDDERYKAVEREKDRKDFFENYIDELRQKERVKAQEQRKQNVMEYRRFLESCDFIKANSQWRKVQDRLETDERCSRLDKIDRLEIFQEYIRDLEKEEEEQRRIQKEELRKTERKNRDEFRKLVEGHVAAATLTAKTHWRDYCMMVKDSPPFLAVASNTSGPTPKDLFEDVAEELQKQYDDDKVRVKDAVKLRKICLASTWTLEDLKAAILEDISSPPISDVNLKLIFEELLERVKEKEEKEAKKRKRLADDFFDLLHSMKEITSSSAWEDCKHLLESSQEFSSIGDEDICKGIFDEYVKQLKGDAKEKERRRKEDKAKKEKERDERERRKAKHGRDKERGYEREKEEHSREGPSEAHGDLSEVHDENENKRSGKEDSKKHRKRHQSSVDNSNETEKDRTKTHRHSGDRRKSKKHASTPESDNESRHKRHKRDHRNGSRRNLDPEELEDGEFGERESQ
Length991
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-1.021
Instability index58.07
Isoelectric point6.21
Molecular weight112633.97
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13025
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.49|      34|      38|     186|     223|       1
---------------------------------------------------------------------------
  186-  219 (67.26/34.68)	PKPTEEALTDWIEHTSANGRRYYYNRKTRQSSWE
  227-  260 (64.23/37.87)	PIERADASTNWKEYTSPDGRKYYYNKVTNLSTWS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     410.92|      65|      65|     716|     780|       2
---------------------------------------------------------------------------
  388-  428 (26.36/14.18)	...........................................KV.SSLD...MVSSEGV.......STQ.NA.DET.........VKDVV..V....SEKI..N.NalEEKAID
  437-  494 (59.62/44.72)	KQE..AKDA....F.....KalLESANVGSDW.....TWD.QAMR.VIIN...DKRYGAL.......RTLgER.KQA.........FNEFL...................GQKKK
  501-  573 (55.34/40.79)	RIK..QKKAreeyK.....K..MLEECLELTS.....STR.WSKAvTMFE...D..............DE.RY.KAVerekdrkdfFENYIDEL....RQKE..RvK..AQEQRK
  579-  638 (63.67/48.44)	YRR..FLES....C.....D..FIKA..NSQWrkvqdRLEtDERC.SRLD...KIDRLEI..........................FQEYI.RD....LEKE..E.E..EQRRIQ
  652-  714 (55.02/40.49)	EFRklVEGH....V.....A..AATLTAKTHW.......R.DY.C.MMVK...D..SPPFlavasntSGP.TP.KDL.........FEDVAEEL....QKQY..D.D........
  716-  780 (98.93/80.81)	KVR..VKDA....V.....K..LRKICLASTW.....TLE.DLKA.AILE...DISSPPI.......SDV.NL.KLI.........FEELLERV....KEKE..E.K..EAKKRK
  783-  853 (51.99/37.72)	......ADD....FfdllhS..MKEITSSSAW.......E.DCK..HLLEssqEFSS..I.......GDE.DIcKGI.........FDEYVKQLkgdaKEKErrR.K..EDKAKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      97.86|      16|      16|      78|      93|       3
---------------------------------------------------------------------------
   29-   41 (17.90/ 6.67)	..SVP.PQ.QFQPVGRG
   62-   76 (25.89/13.10)	MQQLP.AR.PGHILPPP
   78-   93 (30.38/16.71)	SASLPAAQ.PNQHVNPG
   95-  110 (23.69/11.33)	SVPQPNIQaPNNYF.PG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     135.58|      28|      29|     916|     943|       4
---------------------------------------------------------------------------
  878-  905 (42.64/20.55)	EKEEHSREGPSEAHGDLSEVHDENENKR
  916-  943 (45.96/22.69)	KRHQSSVDNSNETEKDRTKTHRHSGDRR
  946-  973 (46.99/23.36)	KKHASTPESDNESRHKRHKRDHRNGSRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.92|      27|      29|     289|     317|       5
---------------------------------------------------------------------------
  281-  307 (52.79/32.74)	QSEVSSHFP.APVPPASKAQ....SGAD....TSST
  310-  345 (36.13/14.81)	QGASSSPVPvAPVPSTSKIEsvvvSGSDlpvaTSST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.15|      18|      18|     147|     164|       6
---------------------------------------------------------------------------
  120-  138 (18.42/ 6.88)	YtfAP..SSYGQVTVsHNAMA
  147-  164 (32.87/17.12)	Q..APNVPVGGQVGI.HVSQS
  166-  180 (19.85/ 7.90)	.....SVTSAQQIGE.HPSAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.84|      12|      20|     355|     366|       9
---------------------------------------------------------------------------
  355-  366 (19.87/12.68)	VED.TVTPSVAVS
  375-  387 (16.97/ 9.75)	VADaATTPMNNIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13025 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DAKEKERRRKEDKAKKEKERDERERRKAKHGRDKERGYEREKEEHSREGPSEAHGDLSEVHDENENKRSGKEDSKKHRKRHQSSVDNSNETEKDRTKTHRHSGDRRKSKKHASTPESDNESRHKRHKRDHRNGSRRNLDPEELEDGEFGERESQ
2) LAREQVEMASAKGPQSEVSSHFPAPVPPASKAQSGADTSSTIIQGASSSPVPVAPVPSTS
3) MDPSQNFPPPMTGQFRPVVPSQQPQQFVSVPPQQFQPVGRGVTVMNAGFPSQTPQPQFPQVMQQLPARPGHILPPPPSASLPAAQPNQHVNPGASVPQPNIQAPNNYFPG
4) SHNAMAQYQPMAQLQAPNVPVGGQVGIHVSQSTSVTSAQQIGEHPSASTATIPPKPTEEALTDWI
838
267
1
133
991
326
110
197










Molecular Recognition Features






MoRF SequenceStartStop




1) ELEDGEF
979
985