<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13023

Description U-box domain-containing protein 33-like isoform X1
SequenceMELHNPAHRDSIPGPRFRPRVDRPANTQFPESAEETGGFNAGEKDKVFIAVGKSVERAVNLLQWTLKRFGGKHICLLHVHQPSPLIPTLLGKLPASQANSRVLSAYRKDEKEQLKKLLENYSNFPRKFKVHISIVTIEANQVHKGIVQLVKRHGIRNLVMGAIPENCMSMKKSSSKSSYAAKYVPCFCDIWFVDKGKLVWTREASEEPCLSTPASQAAVTAKSSRSNSLPHRNSDSLVHPDNLRSNSCLTITFAASSTQLTESIVAQTDVSLSPRLSSFSNLSSPRFTNGSKCASSEMRLSLDSYSKDEDENLYRQLGEASMEAKASKNEALAESLKRQKLELEAMEAINKIKDLESARVHEVKLREKAEEALRATVQEREKLIKEKEEAMEELQRTTRNVTLLNGCVQEANCKHDEVAGKLKLIQASIMTLREEKQRIRRQKLEAVRWLERWRSRGQAGATTCNGFIGIVEDLPELAEFSLADVQTATCNFSESFKIGKGGHGCVYKGEMLGRTVAIKKLYPHNMQGQSEFQQEAQVLSKLQHPHLVTLLGVCPEAWSLVYEYVPNGSLQDRLFRKTSVSPLTWKIRARIVAEISSALCFLHSAKPEKIVHGDLKPENILLDSELSCKICDFGISRLVTEDNLYCPSFHCSTEPKGAFPYSDPEFQRIGVPTPKSDIYAFGLIILQVLTRRPPVGLAGEVRKAISSGKLALILDKSAGEWPMFVARRLVDLGLQCCESYGRDRPDLKPSLVRELGQLHVTEERPVPSFFLCPILQEIMHDPQVAADGFTYEGEALRGWLENGRETSPMTNLKLSHLHLTPNHAIRQAIQNWLCKA
Length836
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.387
Instability index41.51
Isoelectric point8.81
Molecular weight93622.34
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase.
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP13023
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.57|      14|      18|     215|     228|       1
---------------------------------------------------------------------------
  215-  228 (22.54/13.08)	SQAAVTAKSSRSNS
  234-  247 (25.03/15.29)	SDSLVHPDNLRSNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.16|      11|      20|     306|     316|       2
---------------------------------------------------------------------------
  306-  316 (20.72/14.33)	SKDE..DENLYRQ
  327-  339 (14.43/ 7.72)	SKNEalAESLKRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.59|      18|      21|     359|     376|       6
---------------------------------------------------------------------------
  359-  376 (28.00/20.93)	RVHEVKLREKAEEALRAT
  380-  397 (28.59/21.55)	REKLIKEKEEAMEELQRT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.04|      21|     107|     483|     504|       7
---------------------------------------------------------------------------
  483-  504 (34.98/25.43)	ADVQTATCnFSESFKIGKGGHG
  593-  613 (38.06/22.90)	AEISSALC.FLHSAKPEKIVHG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP13023 with Med32 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MELHNPAHRDSIPGPRFRPRVDRPANTQFPESAEETG
1
37

Molecular Recognition Features

MoRF SequenceStartStop
NANANA