<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13018

Description U-box domain-containing protein 33-like isoform X3
SequenceMELHNPAHRDSIPGPRFRPRVDRPANTQFPESAEETGGFNAGEKDKVFIAVGKSVERAVNLLQWTLKRFGGKHICLLHVHQPSPLIPTLLGKLPASQANSRVLSAYRKDEKEQLKKLLENYSNFPRKFKVHISIVTIEANQVHKGIVQLVKRHGIRNLVMGAIPENCMSMKKSSSKSSYAAKYVPCFCDIWFVDKGKLVWTREASEEPCLSTPASQAAVTAKSSSTQLTESIVAQTDVSLSPRLSSFSNLSSPRFTNGSKCASSEMRLSLDSYSKDEDENLYRQLGEASMEAKASKNEALAESLKRQKLELEAMEAINKIKDLESARVHEVKLREKAEEALRATVQEREKLIKEKEEAMEELQRTTRNVTLLNGCVQEANCKHDEVAGKLKLIQASIMTLREEKQRIRRQKLEAVRWLERWRSRGQAGATTCNGFIGIVEDLPELAEFSLADVQTATCNFSESFKIGKGGHGCVYKGEMLGRTVAIKKLYPHNMQGQSEFQQEAQVLSKLQHPHLVTLLGVCPEAWSLVYEYVPNGSLQDRLFRKTSVSPLTWKIRARIVAEISSALCFLHSAKPEKIVHGDLKPENILLDSELSCKICDFGISRLVTEDNLYCPSFHCSTEPKGAFPYSDPEFQRIGVPTPKSDIYAFGLIILQVLTRRPPVGLAGEVRKAISSGKLALILDKSAGEWPMFVARRLVDLGLQCCESYGRDRPDLKPSLVRELGQLHVTEERPVPSFFLCPILQEIMHDPQVAADGFTYEGEALRGWLENGRETSPMTNLKLSHLHLTPNHAIRQAIQNWLCKA
Length804
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.380
Instability index39.89
Isoelectric point8.78
Molecular weight90129.55
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13018
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.23|      31|     116|      87|     126|       1
---------------------------------------------------------------------------
   87-  118 (47.64/24.66)	PTLlGKLPASQANSRVLSAYRKDEKEQLKKLL
  208-  232 (40.36/15.71)	PCL..STPASQA...AVTA..KSSSTQLTESI
  258-  285 (41.23/27.57)	....GSKCASSEMRLSLDSYSKDEDENLYRQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.04|      21|     107|     451|     472|       2
---------------------------------------------------------------------------
  451-  472 (34.98/27.41)	ADVQTATCnFSESFKIGKGGHG
  561-  581 (38.06/24.68)	AEISSALC.FLHSAKPEKIVHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.52|      27|     287|     362|     393|       3
---------------------------------------------------------------------------
  362-  393 (42.25/35.98)	LQRTTRNVTL.LNGCVQEANCkhdevAGKLKLI
  654-  681 (41.27/23.93)	LQVLTRRPPVgLAGEVRKAIS.....SGKLALI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13018 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MELHNPAHRDSIPGPRFRPRVDRPANTQFPESAEETG
1
37










Molecular Recognition Features






MoRF SequenceStartStop




NANANA