<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13009

Description pre-mRNA-processing protein 40A-like isoform X1
SequenceMANNSQPSSAQPHWPPAVGSMGPQSYGSPLSSQFRPVVPTQQGQHFVPAASQQFRPVGQVPSPNIGMPAVQNQQMQFSQPMQQFPPRPNQPGLSTPSQQPIQVQYGQTNRPLTSEPPQSHQSAPPLNSHMPGVGVPGVPPSSYGFAPSSFGLPQNNVSAPSQFHPISQVHAPVAPVAGQPWLSTGNQNVSLATPTQHTSQQPPPSSADTNANVPSLTPQSSDWQEHTSADGRRYYYNKRARQSSWEKPLELMTPIERADASTVWKEFTTPEGRKYYHNKVTKESKWTIPEELKLAREQAQAGASQGTPSGSGVAPQALVATAVSAAETPTTAIPVSSNTLQDSSPVSVTPVANPSPTSVSGPTTGPVAQSAAMSATGVQLPVVSVTPVPAVPSRGSTVSAPSVGANTAVTRSSETTATQDTMHFADGASAQDIEEAKKGMTTAGKVNMTPVEEKVPDDEPLVYANKLEAKNAFKSLLESANVQSDWTWEQTMREIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMRQKKAREEFTKMLEESKELTSSMRWSKAQSLFENDERFKAVERARDREDLFENYIVDLERKEREYAAEEKRRNIAEYRKFLESCDFIKANSQWRKVQDRLEDDERCSRLEKIDRLLIFQDYIHDLEKEEEEKKKMQKEQLRRAERKNRDAFRKLMEEHVADGTLTAKTYWRDYCLKVKELPQYLAVASNTSGSTPKDLFEDVAEELDKQYHEHKTRIKEAMKTGKVTMVYSWTFEDFKAAISEDVGSSSISDINLKLVYDELLERAKEKEEKEAKKRQRLADDFTRLLHTYKEITASSDWEESKPLFEESQEYRSIAEESFRREIFEEYITHLQEKAKEKERKREEEKAKKEKDREEKDKRKEKEKERKEKEREREREKGKDRSKKDETDSENLDISDSYGHKEEKKKEKEKDRKHRKRHAADDGSSDKDDREESKKSRRHGSDRKKSRKHAHSPDSDSESRHRKHKRDHRDGSRRNSGYEELEDGELGEDGEIQ
Length1026
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-1.152
Instability index58.52
Isoelectric point6.74
Molecular weight116532.76
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13009
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     149.86|      36|      38|     216|     251|       1
---------------------------------------------------------------------------
  199-  230 (38.44/18.65)	......SQQPPPSSADTNANV..psLTP.....QSSDWQEHTSAD
  231-  271 (58.89/32.77)	GRRYYYNKRARQSSWEKPLEL....MTPieradASTVWKEFTTPE
  272-  311 (52.53/28.37)	GRKYYHNKVTKESKWTIPEELklarEQA.....QAGASQGTPSGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     112.17|      17|      17|     870|     886|       2
---------------------------------------------------------------------------
  565-  581 (19.17/ 6.46)	NDERFKAVERARDREDL
  870-  886 (26.07/11.70)	EKERKREEEKAKKEKDR
  888-  904 (25.32/11.13)	EKDKRKEKEKERKEKER
  934-  950 (22.49/ 8.98)	KEEKKKEKEKDRKHRKR
  977-  993 (19.12/ 6.42)	KKSRKHAHSPDSDSESR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      90.73|      14|      17|      24|      37|       3
---------------------------------------------------------------------------
   24-   37 (27.02/12.07)	QSYGSPLS.....SQFRPV
   44-   57 (23.61/ 9.66)	QHFVPAAS.....QQFRPV
  120-  133 (20.59/ 7.51)	HQSAPPLN.....SHMPGV
  148-  166 (19.52/ 6.75)	SSFGLPQNnvsapSQFHPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     159.69|      31|      34|     321|     351|       4
---------------------------------------------------------------------------
  321-  351 (51.82/35.82)	TAVS.AAETPTT.............AIPVSSNTLQDSSPVSVTPV
  357-  378 (36.18/22.41)	TSVS.G...PTT.............G.PVA.....QSAAMSATGV
  379-  406 (40.06/25.74)	QLPV.VSVTPVP.............AVPSRGSTV...SAPSVGAN
  407-  451 (31.63/18.50)	TAVTrSSETTATqdtmhfadgasaqDIEEAKKGMTTAGKVNMTPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     414.07|      94|     140|     463|     556|       5
---------------------------------------------------------------------------
  463-  533 (99.76/58.43)	..................................................................YANKLEAKNAFKSLLESAN.VQSDWTWEQTMREIINDKRYGALKTLGERKQA...................FNEYLG..QRKKLE....AEERRMRQ
  534-  602 (48.98/24.80)	KKAREEFTKMLEE...SKELTSSMRW.......................................sKAQSL...............................................fenderfkaverardredlFENYIV..DLERKEreyaAEEKR...
  603-  668 (77.70/43.82)	.......................................................................RNIAEYRKFLESCDfIKANSQWRKVQDRLEDDERCSRLEKI.DRLLI...................FQDYIH..DLEKEE....EEKKKMQK
  676-  809 (112.27/66.71)	RKNRDAFRKLMEEhvaDGTLTAKTYWrdyclkvkelpqylavasntsgstpkdlfedvaeeldkqyHEHKTRIKEAMKT.GKVTM.VYS.WTFEDFKAAISEDVGSSSISDI.NLKLV...................YDELLE..RAKEKE....EKEAKKRQ
  810-  867 (75.36/42.27)	RLA.DDFTRLLHT...YKEITAS.................................................................SDWEESKPLFE..ESQEYRSIAEESFRREI...................FEEYIThlQEK...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.53|      25|      29|      63|      87|       6
---------------------------------------------------------------------------
   63-   87 (47.70/28.92)	PNIGMPAVQNQQMQFSQ...PMQQFPPR
   91-  118 (41.03/23.80)	PGLSTPSQQPIQVQYGQtnrPLTSEPPQ
  180-  196 (23.79/10.58)	PWLSTG...NQNVSLAT...PTQ.....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13009 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KAKEKERKREEEKAKKEKDREEKDKRKEKEKERKEKEREREREKGKDRSKKDETDSENLDISDSYGHKEEKKKEKEKDRKHRKRHAADDGSSDKDDREESKKSRRHGSDRKKSRKHAHSPDSDSESRHRKHKRDHRDGSRRNSGYEELEDGELGEDGEIQ
2) MANNSQPSSAQPHWPPAVGSMGPQSYGSPLSSQFRPVVPTQQGQHFVPAASQQFRPVGQVPSPNIGMPAVQNQQMQFSQPMQQFPPRPNQPGLSTPSQQPIQVQYGQTNRPLTSEPPQSHQSAPPLNSHMPGVGVPGVPPSSYGFAPSSFGLPQNNVSAPSQFHPISQVHAPVAPVAGQPWLSTGNQNVSLATPTQHTSQQPPPSSADTNANVPSLTPQSSDWQEHTSADGRRYYYNKR
3) PVVSVTPVPAVPSRGSTVSAPSVGANTAVTRSSETTATQDTMHFADGASAQDIEEAKKGMTTAGKVNMTPVEEKVPDDEPLVY
4) WTIPEELKLAREQAQAGASQGTPSGSGVAPQALVATAVSAAETPTTAIPVSSNTLQDSSPVSVTPVANPSPTSVSGPTTGPVAQSAAMSAT
867
1
381
286
1026
239
463
376










Molecular Recognition Features






MoRF SequenceStartStop




1) GYEELED
2) KDDREESKKSRRH
3) KEKDRKHRKRHAADD
4) RHRKHKRDHR
5) RKKSRKH
1010
960
941
993
976
1016
972
955
1002
982