<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13006

Description mediator of RNA polymerase II transcription subunit 19a-like isoform X1
SequenceMDAGGNKFGGGPRELSGVVDLISRYKLLPHHDFFCKRPLPLSIADTHYLHNVAGDTEIRKGEGMQLDQLNQNTSYNRDTNFRIQPFDFDILKEAFQLRETTPVELPPTEKGMPTIAGKSKSEVKDKERKHKKHKDRDKEKDKEHKKHKHRHKDKDRSKDKDKEKKKDRSGHYDSGADHLKKHHEKKRKHDGDEDRNDINRHKKSKSKLVN
Length210
PositionHead
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.05
Grand average of hydropathy-1.600
Instability index38.60
Isoelectric point9.62
Molecular weight24551.31
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
transcription factor binding	GO:0008134	IBA:GO_Central

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13006
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.80|      15|      15|     124|     138|       1
---------------------------------------------------------------------------
  124-  138 (28.86/ 8.61)	KDKERKHKKHKDRDK
  181-  195 (26.94/ 7.66)	KHHEKKRKHDGDEDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.44|      15|      17|     139|     153|       2
---------------------------------------------------------------------------
  139-  153 (29.22/11.20)	EKDKEHKKHKHRHKD
  159-  173 (28.21/10.59)	DKDKEKKKDRSGHYD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13006 with Med19 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LRETTPVELPPTEKGMPTIAGKSKSEVKDKERKHKKHKDRDKEKDKEHKKHKHRHKDKDRSKDKDKEKKKDRSGHYDSGADHLKKHHEKKRKHDGDEDRNDINRHKKSKSKLVN
97
210










Molecular Recognition Features






MoRF SequenceStartStop




1) DKEKDKEHKKHKHRHKDKDRSKDKDKEKKKDRSGHYDSGADHLKKHHEKKRKH
2) KHKKHKD
137
129
189
135