<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP13002

Description mediator of RNA polymerase II transcription subunit 16-like isoform X1
SequenceMNQQPGLGDNKESEEEPVAQPVDSAVKLGLEKPVGSEPVSGVAEDEVVVSSSGKSEDTVMEEDPVNPATVFCIWLKQPKSNLRYKMRVPELCRNFSAVAWCGKLNAIACATETCARIPSSNANPPFWIPIQIVIPERPTECAVFNVTADSPRDSVQFIEWSPTSCPRALLIANFHGRVTIWTQPSQGPAHLVRDASFWKREHEWRQDIAVVTKWLSGVSPYRWLSSKSINPANSKSTFEEKFLSQQSQNSARWPNFLCVCSVFSSGSVQLHWSQWPPTQGSVARKWFCTSKGILGAGPSGIMAADAIITDSGAMHVAGVPIVNPSTVVVWEVTPGTGNGFQATAKTSTSNGIPPSVNPPNWAGFAPLAAYLFSWQEYLISEAKQGKKTADQDFNDVVSLHCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRGGSVIAVVIVEGQYMSPYDPDEGPTITGWRVQRWESSLQPVVLHNIFGNPSSSFGGQAPKQTVWLSKVDTSIPPTNDFKSHQAAAAGPTSDSRKASDSSSEKLKRVSFDPFDLPSDVRTLARIVYSAHGGEIAISFLRGGVHIFSGPNFSAVDNYQINVGSAIAAPAFSSTSCCSASVWHDTSKDRTMLKIIRVLPPAISSSQIKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQRAAEDGIVSLNSVIAVLDADFHSLPSIQHRQQYGPSLDRIKCRLLEGTNAQEVRAMVLDMQARLLLDMLGKGIESALVNPSALVSEPWQASGETLSSIDPEAMAVDPALVQSIQAYVDAVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNMVTSPTQSSATPATSQAGQSGTTSSTGSTQMQAWVQGAIAKISGSTDGVSTSTPNTISGPSSFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRALQPRFAQRNTDANPQKNQPGAPGKMEEVNSVAAKPTTMTRPDEAHGARAGQLVPGAKGAEEGPRGLKIGSGNAGQGYTFEEVKVLFLILMDLCRRTSGLPHPLPVSQVGSSSIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPSSEEWHRRNMFGGPWSDLEDMSPGDDIPRLSNSIDMPDTSSMESSNVHYGVQTLWPRKRRLSERDAAFGLNTSVDLGAYLGIMGSRRDVVTAVWKIGLEGVWYKCMRCLRQTSAFASADSTHQPSQNERVSWWISRWAYGCPMCGGPWVRVV
Length1248
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.08
Grand average of hydropathy-0.211
Instability index43.66
Isoelectric point6.51
Molecular weight135115.92
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP13002
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.82|      19|      21|     833|     853|       1
---------------------------------------------------------------------------
  835-  853 (33.66/18.62)	PTQSSATPATSQ...AGQSGTT
  855-  876 (29.16/ 9.88)	STGSTQMQAWVQgaiAKISGST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     497.36|     166|     568|     474|     673|       2
---------------------------------------------------------------------------
  474-  673 (249.18/209.72)	SSLQpVVLHNIFGN....PSSsfggqapkqtvwlskVDTSIPP..TNDFKSHQAAAAGPTSDSRKASDSSSEKLKRVSF.DPF.DL....P.SDVRTLARIVYSAHGGEIAISFLRGGVHIFsGPN...FSAVD.....NYQINVGSAIAapAFSSTSCCSASVWhdtskdRTML.....KIIRVLPPaisSSQIKANSSTWERAIAERF.WWsllvgVDWWdAVGC
 1045- 1237 (248.18/143.28)	SSIQ.VRLHYIDGNytvlPEV...............VEASLGPhmQNMPRPRGADAAGLLLRELELHPSSEEWHRRNMFgGPWsDLedmsPgDDIPRLSNSIDMPDTSSMESSNVHYGVQTL.WPRkrrLSERDaafglNTSVDLGAYLG..IMGSRRDVVTAVW......KIGLegvwyKCMRCLRQ...TSAFASADSTHQPSQNERVsWW.....ISRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.35|      14|      19|     238|     254|       3
---------------------------------------------------------------------------
  222-  235 (22.76/ 6.18)	RWLSSKSINPANSK
  241-  254 (26.59/17.73)	KFLSQQSQNSARWP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.38|      15|      23|     160|     181|       4
---------------------------------------------------------------------------
  172-  188 (25.33/16.31)	ANFHGRVTIW.........tqPSQGP
  195-  220 (21.04/ 7.77)	ASFWKREHEWrqdiavvtkwlSGVSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.78|      17|      21|     784|     804|       7
---------------------------------------------------------------------------
  788-  804 (28.66/21.13)	IQAYVDAVLDLASHFIT
  806-  822 (30.12/12.77)	LRRYASFCRTLASHAVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.58|      29|     232|      98|     127|      10
---------------------------------------------------------------------------
   98-  127 (56.09/34.16)	VAWC...GKLNAI.ACA.TETCARIPSSnANPPFW
  328-  361 (45.49/22.88)	VVWEvtpGTGNGFqATAkTSTSNGIPPS.VNPPNW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.29|      10|      19|     753|     762|      11
---------------------------------------------------------------------------
  753-  762 (17.09/ 8.58)	VNPSALVSEP
  773-  782 (18.20/ 9.61)	IDPEAMAVDP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP13002 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQRNTDANPQKNQPGAPGKMEEVNSVAAKPTTMTRPDEAHGARAGQLVPGAKGAEEGPRGLKIGS
2) GTGSNRNMVTSPTQSSATPATSQAGQSGTTSSTGST
940
824
1004
859










Molecular Recognition Features






MoRF SequenceStartStop




1) AVKLGLEK
2) NKESEEEPVAQPVD
25
10
32
23