<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12998

Description heat shock 70 kDa protein
SequenceMAAKAEGKAIGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRRFSDPAVQADMKHWPFKVVAGPGDKPMIVVNYKGEEKQFAPEEISSMVLVKMKEVAEAYMGQTVKNAVITVPAYFNDSQRQATKDAGSISGLNILRIINEPTAAAIAYGLDKKASRSGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFKRKHKKDISTNARALRRLRTACERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDSKIDKSQVDEVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELTGIPPAPRGVPQINVCFDIDANGILNVSAEDKTAGVKNKITITNDKGRLSKEEIERMVQEAERYKAEDEEVKKKVEAKNGLENYAYNMRNTVKDDKFAGKLDPAEKQKIEKAIDDTIEWLDGNQLAEVDEFEDKLKELEGICNPIIAKMYQGGAGGDVPMGGGAEMPNGGGSGGSGAGPKIEEVD
Length652
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.424
Instability index34.37
Isoelectric point5.15
Molecular weight71383.06
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12998
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.99|      19|      74|     448|     466|       1
---------------------------------------------------------------------------
  448-  466 (31.69/23.55)	VYEGERARTKDNNLLGKFE
  525-  543 (27.84/19.66)	VQEAERYKAEDEEVKKKVE
  552-  569 (28.46/20.29)	AYN.MRNTVKDDKFAGKLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.14|      21|     106|      40|      60|       4
---------------------------------------------------------------------------
   40-   60 (37.87/23.92)	TTPSYVAFTDTERLIGDAAKN
   64-   78 (21.79/10.89)	MNPQNTVF.DAKRLIG.....
  149-  164 (29.47/17.11)	TVPAY..FNDSQR...QATKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.08|      45|     189|     170|     218|       6
---------------------------------------------------------------------------
  170-  218 (62.76/51.49)	GLNILRIINePTaAAIAYGLDKKAS.RSGEKNVLIFDLggGTFDVSLLTI
  362-  407 (72.32/43.44)	GKELCKSIN.PD.EAVAYGAAVQAAiLSGEGNEKVQDL..LLLDVTPLSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12998 with Med37 domain of Kingdom Viridiplantae
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