<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12995

Description U-box domain-containing protein 34-like isoform X1
SequenceMEMSVGSANTGGSPTKLTTVAIAVKSGSGSRRAVRWVVENLKADRFVLVHVMPAVTSIPTPSGDQIPITEMDENVVAMYVQEVKLKFEQVFIPFLNLFKTSKVETVVLEDDYPAIGLLRYISEFGIQTLVLGSYSSNYITRKLKGPGVPNSVLKCAPDTCDIRVVYRQRIITKQANPLWTSGTSSSGFKKHIYGPINASAESTAQNSFGTASSFELNYPYLHAFSSRGSLTNASSISHCHSLGSTQSEKLNLQAEVEQLRLELQNTVAMYKEAREELVDTQNKVRLLSSECLEEASRVNAAQEREEAFRKIAAEEKVKLLQAMKDVEEAKHLLSREANRRQMAELNAHKESLEKQKFVDALFCCDRRYRKYTRDEIEVATDFFSVSNVIGQGGYGKVYKCSLHRTPVAVKVLQSDALDRKEEFLREIEVLSQLHHPHIVLLLGACPENGCLVYEYLENGSLEEHILQKSGKPPLPWFIRFRIVFEVASGLAFLHNSKPDPIVHRDLKPGNILLDRNYVSKIGDVGLAKLISDVVPDNITMYKDSILAGTLFYMDPEYQRTGTVRPKSDLYALGLTTLQLLTARHPNGLLLAVENAIKNCCLADILDKSITDWPLAETEELARIALKCSKLRCRDRPDLDTEVLPILKRLVGVADASLKLGKSNVYAPSYYFCPILQEVMDDPHIAADGFTYEHRAIKAWLGKHNVSPVTKRQLQHSVLTPNHTLRSAIHDWKSRVTLSTT
Length740
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.226
Instability index42.86
Isoelectric point8.06
Molecular weight82793.00
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12995
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.37|      27|     148|     424|     451|       1
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  424-  451 (44.96/29.87)	LREIEVLSQlHHPHIVLL.LGACPENGCL
  574-  601 (42.41/23.87)	LTTLQLLTA.RHPNGLLLaVENAIKNCCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.40|      31|      32|     267|     297|       2
---------------------------------------------------------------------------
  265-  295 (50.41/38.67)	NTVAMYKEAREEL..VDTQNKVRLLSS.ECLEEA
  296-  329 (37.99/27.26)	SRVNAAQEREEAFrkIAAEEKVKLLQAmKDVEEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.10|      41|     394|      85|     125|       7
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   85-  125 (70.97/37.94)	LKFEQVF..IPFLNLFKTSKVETVVLEDDYPAIGLL..RYISEFG
  478-  522 (63.13/33.12)	IRFRIVFevASGLAFLHNSKPDPIVHRDLKPGNILLdrNYVSKIG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12995 with Med32 domain of Kingdom Viridiplantae
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