<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12993

Description mediator of RNA polymerase II transcription subunit 25-like isoform X3
SequenceMAEKQLIVAVEGTAAMGPYWHIVVSDYLDKIIRCFCSSELTGQRSGWTKDVDIFLQWLSAIPFSGGGFNDAAIAEGLSEALMMFPIASNGNQTPQNVDGQRHCILVAASNPYPLPTPVYRPQIQNLEQVENSEAQTESRLSDAETVARSFAQCSVSLSVICPKQLAKLKAIYSAGKQNPRAADPPVDNVKNSQFLVLISENFMEGRAALSRSGLPSLATNQSPVKMDMASVTSVTGPPPSSVNGSMVGRLPVSVGNVATATVKVEPTTITSMATGPAFSHVPSVPRAPSQAIPTLQTSSPLTNTLEGMTSGDNMQELKPSVSGMTQPSRPVPPAAANVNILNNLSQARVMSSAALTGGTSIGLQSMVQTPVAMHMSNMISSGMASSVPPAHTVLSSGQPTMTSLTGSGALTGAAQVLPNSGLSSFSSATSNVAGNSNIGISQPMGNVQGAVNIGQSVPGMSQGNHSGTQMMQSGVGMSQNMSALGQSTVSSGNGTMIPTPGMSQQVQSGMQTLGVSNSSAASMPLSQQTSSALQSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASETLAAHWPQTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLGQLQEKKLCAVIQLPQQTLLLSVSDKACRLIGMLFPGLHSSNTPPGLHPSLDKPKKLNEMDMVVFKPQMSSQQQLQLQQQQMQPQLQQQQQQQNPQLQQQQLPHLQQQQLPQLQQQQQQQQLPQLQQQQLSQLQQQQQQQKQQQQQQQQSQHPQMQQQQLSQQQQMVGSGMGPAYVQGPG
Length796
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.04
Grand average of hydropathy-0.350
Instability index61.47
Isoelectric point8.85
Molecular weight85075.41
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12993
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     120.10|      23|      25|     700|     724|       1
---------------------------------------------------------------------------
  700-  723 (41.79/14.14)	...PQLQQQQQQ.QN.PQLQQQQLPhlQQ
  724-  746 (31.94/ 6.29)	QqlPQLQQQQQQ.QQlPQLQQQQL.....
  756-  779 (46.37/12.43)	Q..KQQQQQQQQsQH.PQMQQQQLS..QQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     244.31|      48|      54|     184|     231|       3
---------------------------------------------------------------------------
  184-  213 (39.52/17.18)	....................................PPVDNV..............KN.S.QFLVLISENFMEGRAALSRS...G
  214-  253 (50.13/23.85)	LPSLATNQSPVKMD......MASV.......tsvtgPPPSSV..............NG.S...........MVGRLPVS......
  254-  311 (44.32/20.20)	VGNVAT..ATVKVEpttitsMATG............PAFSHVpsvprapsqaiptlQT.S.SPLT....NTLEGMT....S...G
  312-  362 (38.24/16.37)	.....DNMQELK.........PSV.sgmtqpsrpvpPAAANV...................NILNNLSQARVMSSAALTGGtsiG
  363-  408 (43.96/19.97)	LQSMV..QTPVAMH......M...snmissgmassvPPAHTV..............LS.SgQP..........TMTSLTGS...G
  417-  445 (28.15/10.02)	LPN.........SG......LSSF...........sSATSNV..............AGnS.NI..GISQP..MG...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     214.45|      52|      54|     473|     524|       4
---------------------------------------------------------------------------
  473-  508 (53.49/26.52)	.................................SG..VG.........MSQNMSALGQST......VSSGNGTMIPTPGMSQQVQS
  509-  554 (57.43/29.13)	GMQTLGVSNSSAASMP................lS...............QQTSSAL.QSAqskyvkVWEGN........LSGQRQG
  564-  630 (50.89/24.81)	GYRSASASETLAAHWPqtmqivrlisqdhmnnkQY..VGkadflvfraMNQH.GFLGQ................LQEKKLCAVIQL
  631-  670 (52.64/25.97)	PQQTLLLSVSDKAC.....................rlIG.........ML..FPGLHSSN......TPPGLHPSLDKP........
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12993 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KQQQQQQQQSQHPQMQQQQLSQQQQMVGSGMGPAYVQGPG
2) LSRSGLPSLATNQSPVKMDMASVTSVTGPPPSSVNGSMVGR
3) NMISSGMASSVPPAHTVLSSGQPTMTSLTGSGAL
4) TITSMATGPAFSHVPSVPRAPSQAIPTLQTSSPLTNTLEGMTSGDNMQELKPSVSGMTQPSRPVPPAAANVNI
5) VQGAVNIGQSVPGMSQGNHSGTQMMQSGVGMSQNMSALGQSTVSSGNGTMIPTPGMSQQVQSGMQTLGVSNSSAASMPLSQQT
757
209
377
268
447
796
249
410
340
529










Molecular Recognition Features






MoRF SequenceStartStop




1) PQMQQQQLSQ
2) VGSGMGPAYVQGPG
769
783
778
796