<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12992

Description mediator of RNA polymerase II transcription subunit 25-like isoform X2
SequenceMAEKQLIVAVEGTAAMGPYWHIVVSDYLDKIIRCFCSSELTGQKNSTSNVEFSLVTFNTHGSYCACLVQRSGWTKDVDIFLQWLSAIPFSGGGFNDAAIAEGLSEALMMFPIASNGNQTPQNVDGQRHCILVAASNPYPLPTPVYRPQIQNLEQVENSEAQTESRLSDAETVARSFAQCSVSLSVICPKQLAKLKAIYSAGKQNPRAADPPVDNVKNSQFLVLISENFMEGRAALSRSGLPSLATNQSPVKMDMASVTSVTGPPPSSVNGSMVGRLPVSVGNVATATVKVEPTTITSMATGPAFSHVPSVPRAPSQAIPTLQTSSPLTNTLEGMTSGDNMQELKPSVSGMTQPSRPVPPAAANVNILNNLSQARVMSSAALTGGTSIGLQSMVQTPVAMHMSNMISSGMASSVPPAHTVLSSGQPTMTSLTGSGALTGAAQVLPNSGLSSFSSATSNVAGNSNIGISQPMGNVQGAVNIGQSVPGMSQGNHSGTQMMQSGVGMSQNMSALGQSTVSSGNGTMIPTPGMSQQVQSGMQTLGVSNSSAASMPLSQQTSSALQSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASETLAAHWPQTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLGQLQEKKLCAVIQLPQQTLLLSVSDKACRLIGMLFPGDMVVFKPQMSSQQQLQLQQQQMQPQLQQQQQQQNPQLQQQQLPHLQQQQLPQLQQQQQQQQLPQLQQQQLSQLQQQQQQQKQQQQQQQQSQHPQMQQQQLSQQQQMVGSGMGPAYVQGPG
Length799
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.04
Grand average of hydropathy-0.316
Instability index61.61
Isoelectric point8.64
Molecular weight85384.66
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12992
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     163.19|      25|      25|     703|     727|       1
---------------------------------------------------------------------------
  526-  562 (29.52/ 6.37)	PGMSQQVQsgmqtlgvsnssaA.SM.P.LSQQTSSALQSA
  703-  727 (56.20/18.35)	PQLQQQQQ.............Q.QN.PQLQQQQLPHLQQQ
  730-  749 (32.52/ 7.71)	PQLQQQQQ.............Q.QQlPQLQQQQL......
  760-  783 (44.95/13.30)	KQQQQQQQ.............QsQH.PQMQQQQLS..QQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     245.12|      55|      56|     380|     434|       2
---------------------------------------------------------------------------
  239-  271 (32.51/11.56)	.............................G.........LPSL..AtnQSPVKM..DMASV....TS..........vTG........PPPSS............VNGS
  291-  377 (51.41/22.84)	EPTTITSMATGPAFSHVPSV.........PrapsqaiptLQT......SSPLTN..TLEGM....TSgdnmqelkpsvSGMtqpSRPVPPAAAnvnilnnlsqarVMS.
  378-  422 (73.33/35.93)	..........SAALTGGTSI.........G.........LQSM..V..QTPVAM..HMSNM....IS...........SGM...ASSVPPAHT............VLSS
  423-  467 (44.76/18.88)	GQPTMTSLTGSGALTGAAQV.....lpnsG.........LSSFssA..TSNVAG..N.SNI..................GI...S........................
  468-  524 (43.11/17.89)	.QP.MGNVQ..GAVNIGQSVpgmsqgnhsG.........TQ.M..M..QSGVGMsqNMSALgqstVS...........SGN...GTMIP....................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.40|      37|      50|     590|     634|       6
---------------------------------------------------------------------------
  590-  634 (55.48/53.76)	GYRSASASETLAA..HWPQ.TM......QIVRLISQdhmnnkQYVGkaDFLVFR
  640-  685 (51.93/31.31)	GFLGQLQEKKLCAviQLPQqTLllsvsdKACRLIGM......LFPG..DMVVFK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12992 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LSRSGLPSLATNQSPVKMDMASVTSVTGPPPSSVNGSMVGR
2) NMISSGMASSVPPAHTVLSSGQPTMTSLTGSGAL
3) QQQQQQQQSQHPQMQQQQLSQQQQMVGSGMGPAYVQGPG
4) TITSMATGPAFSHVPSVPRAPSQAIPTLQTSSPLTNTLEGMTSGDNMQELKPSVSGMTQPSRPVPPAAANVNI
5) VQGAVNIGQSVPGMSQGNHSGTQMMQSGVGMSQNMSALGQSTVSSGNGTMIPTPGMSQQVQSGMQTLGVSNSSAASMPLSQQT
235
403
761
294
473
275
436
799
366
555










Molecular Recognition Features






MoRF SequenceStartStop




1) QHPQMQQQQLSQQQQMVGSGMGPAYVQGPG
770
799