<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12990

Description U-box domain-containing protein 33-like isoform X1
SequenceMELLNPPHRDPIPGPSFRPRVDRPANTQFPESAEETGGFNAGEKDKVFIAVGKSVEKAVNLLQWTLKRFGGKHICLLHVHQPSPLIPTLLGKLPASQANSRVLSAYRKDEKEQLKKLLENYSNFPRKFKVHISIFTIEANQVHKGIVELVKGHGIRNLVMGAIPENCMRMKKSSSKSSYAAKYVPCFCDIWFVDKGKLVWMREASEKPCLSTPVGQAAVTAKSSRSNSLPHRNSDSLVHPDDLRSNSCLSITFAASSTRLTESIVAQTDVSLSPRLSSFSNLSIPSFTNGSERASSEMRLSLDSYSKDEDENLYRQLGEACMEAKASKNEALVESLKCQKLESEAMEAINKIKDLKSAHVHEVKLREKAEESLRATVREREKLIKEKEEAMEELQRTTRNITLLNDCVQEANCKHDEVAGKLKLIQASIVTLREEKQRIRRQKLEAVRWLERWRSRGQAGATTCNGFIGIVEDLPELAEFSLADVQTATCNFSESFKIGKGGHGCVYKGEMLGRTVAIKKLYPHNMQGQSEFQQEAQVLSKLQHPHLVTLLGVCPEAWSLVYEYVPNGSLQDRLFRKTSVSPLTWKIRARIVAEISSALCFLHSAKPEKIVHGDLKPENILLDSELSCKICDFGISRLVTEDNLYCPSFHCSTEPKGAFPYSDPEFRRIGVPTPKSDIYAFGLIILQMLTRRPPVGLAGEVRKAISSGKLASILDKSAGEWPMFVARRLVDLGLQCCESYSRDRPDLKPSLVRELGQLHVTEERPVPSFFLCPILQEIMHDPQVAADGFTYEGEALRGWLENGRETSPMTNLKLSHLRLTPNHAIRQAIQNWLCKA
Length836
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.378
Instability index41.67
Isoelectric point8.78
Molecular weight93721.64
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12990
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.30|      45|     749|      13|      61|       3
---------------------------------------------------------------------------
   13-   61 (68.75/55.63)	PGPSF..RPRVDRPANTqfPESAEEtgGFN.AGEKDKVFIAVGKSVEKAVNL
  765-  812 (74.55/46.98)	PVPSFflCPILQEIMHD..PQVAAD..GFTyEGEALRGWLENGRETSPMTNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.66|      23|     361|     269|     292|       4
---------------------------------------------------------------------------
  243-  258 (20.10/ 8.08)	.......LRSNSCLSI.TFAASST
  269-  292 (36.34/26.76)	DVSLSpRLSSFSNLSIPSFTNGSE
  632-  654 (43.23/26.65)	DFGIS.RLVTEDNLYCPSFHCSTE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12990 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MELLNPPHRDPIPGPSFRPRVDRPANTQFPESAEETG
1
37










Molecular Recognition Features






MoRF SequenceStartStop




NANANA