<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12985

Description pre-mRNA-processing protein 40A-like isoform X2
SequenceMANNSQPSSAQPHWPPAVGSMGPQSYGSPLSSQFRPVVPTQQGQHFVPAASQQFRPVGQVPSPNIGMPAVQNQQMQFSQPMQQFPPRPNQPGLSTPSQQPIQFAPSSFGLPQNNVSAPSQFHPMSQVHAPVAPVAGQPWLSTGNQNVSLATPTQHTSQQPPPSSADTNANVPSLTPQSSDWQEHTSADGRRYYYNKRTRQSSWEKPLELMTPIERADASTVWKEFTTPEGRKYYHNKVTKESKWTIPEELKLAREQAQAAASQGTPSGSGVAPQAPVATAVSAAETPTTAIPVSSNTLQDSSPVSVTPVANPSPTSVSGPTTGPVAQSAAMSATGVQLPVVSVTPVPAVPSRGSTVPAPSVGANTAVTRSSETTSTQDTMHFADGASAQDIEEAKKGMATAGKVNMTPVEEKVPDDEPLVYANKLEAKNAFKSLLESANVQSDWTWEQTMREIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMRQKKAREEFTKMLEESKELTSSMRWSKAQSLFENDERFKAVERARDREDLFENYIVDLERKEREYAAEEKRRNIAEYRKFLESCDFIKANSQWRKVQDRLEDDERCSRLEKIDRLLIFQDYIHDLEKEEEEKKKMQKEQLRRAERKNRDAFRKLMEEHVADGTLTAKTYWRDYCLKVKELPQYLAVASNTSGSTPKDLFEDVAEELDKQYHEDKTRIKEAMKTGKVTMVYSWTFEDFKTAISEDVGSSSISDINLKLVYDELLERAKEKEEKEAKKRQRLADDFTRLLHTYKEITASSNWEESKPLFEESQEYRSIAEESFRREIFEEYITHLQDKAKEKERKREEEKAKKEKDREEKDKRKEKEKERKEKEREREREKGKDRTKKDETDSENLDISDSYGHKEEKKKEKEKDRKHRKRHAADDGSSDKDDREESKKSRRHGSDRKKSRKHAHSPDSDSESRHRKHKRDHRDGSRRNSGYEELEDGELGEDGEIQ
Length984
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-1.180
Instability index58.10
Isoelectric point6.69
Molecular weight112246.08
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12985
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.32|      15|      17|      92|     106|       1
---------------------------------------------------------------------------
   92-  106 (29.13/13.59)	GLSTPSQQPIQFAPS
  148-  162 (25.19/10.79)	SLATPTQHTSQQPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     493.56|      65|      65|     497|     561|       2
---------------------------------------------------------------------------
  421-  483 (78.55/46.10)	YANKLEA....K....NAFKSLLE...SANVQSDWTWEQTMREIINDKRYG........AL...KTLGERKQAFNEYLG...................Q...........R.K.KLE
  484-  553 (89.39/53.58)	..AEERRmrqkK.areEFTKMLEE...SKELTSSMRWSKAQSLFENDERFK........AV...ERARDREDLFENYIVD..........L.......E...........R.K.ERE
  554-  620 (90.33/54.23)	YAAEEKR....R.niaEYRKFLES...CDFIKANSQWRKVQDRLEDDERCS........RL...EKI.DRLLIFQDYIHD..........L.......E...........K.E.EEE
  630-  698 (50.47/26.70)	RRAERKN....R...dAFRKLMEEhvaDGTLTAKTYW........RDYCLKvkelpqylAVasnTSGSTPKDLFEDVAEE..........L.......................DKQ
  699-  759 (58.61/32.33)	Y.HEDKT....R........IKEA...MKTGKVTMVYSWT...FE.D..FK..............TAIS.EDVGSSSISDinlklvydelL.......E...........RaK.EKE
  760-  836 (72.49/41.91)	EKEAKKR....QrladDFTRLLHT...YKEITASSNWEESKPLFEESQEYR........SI...AEESFRREIFEEYITH..........LqdkakekE...........R.KrEEE
  837-  900 (53.71/28.94)	KAKKEKD....R...eEKDKRKEK...EKE.....RKEKER....EREREK........GK...DRTKKDETDSEN..............L.......DisdsyghkeekK.K.EKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.34|      24|      24|     265|     288|       3
---------------------------------------------------------------------------
  265-  285 (33.19/17.67)	................TP.S.GSGV.APQAPVATAVS.AAE
  286-  319 (18.95/ 7.05)	TPTtaipvssntlqdsSPvS.VTPV.ANPSP..TSVS.G..
  344-  372 (22.20/ 9.47)	TPV...........paVP.SrGSTVpAPSVGANTAVTrSSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     123.03|      23|      23|      34|      56|       4
---------------------------------------------------------------------------
   14-   34 (31.60/19.72)	...........WPPAVGSMGPQSYGSPLSSQF
   35-   54 (33.28/21.26)	............RPVVPTQQGQHFVPAASQQF
   55-   84 (32.16/20.23)	RPvgqvpspniGMPAVQNQQMQFSQPM..QQF
  122-  146 (25.99/14.59)	HP.....msqvHAPVAPV.AGQPWLSTGNQN.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.73|      36|      38|     174|     209|       5
---------------------------------------------------------------------------
  174-  209 (71.52/40.33)	LTP.....QSSDWQEHTSADGRRYYYNKRTRQSSWEKPLEL
  210-  250 (65.21/36.14)	MTPieradASTVWKEFTTPEGRKYYHNKVTKESKWTIPEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.48|      16|      24|     923|     939|       6
---------------------------------------------------------------------------
  923-  939 (25.56/15.02)	ESKKsRRHGSD.RKKSRK
  949-  965 (23.92/ 9.82)	ESRH.RKHKRDhRDGSRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      27.52|       8|      30|     909|     919|       7
---------------------------------------------------------------------------
  909-  919 (10.46/12.23)	HAaddGSSDKD
  940-  947 (17.06/ 8.33)	HA...HSPDSD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12985 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KAKEKERKREEEKAKKEKDREEKDKRKEKEKERKEKEREREREKGKDRTKKDETDSENLDISDSYGHKEEKKKEKEKDRKHRKRHAADDGSSDKDDREESKKSRRHGSDRKKSRKHAHSPDSDSESRHRKHKRDHRDGSRRNSGYEELEDGELGEDGEIQ
2) MANNSQPSSAQPHWPPAVGSMGPQSYGSPLSSQFRPVVPTQQGQHFVPAASQQFRPVGQVPSPNIGMPAVQNQQMQFSQPMQQFPPRPNQPGLSTPSQQPIQFAPSSFGLPQNNVSAPSQFHPMSQVHAPVAPVAGQPWLSTGNQNVSLATPTQHTSQQPPPSSADTNANVPSLTPQSSDWQEHTSADGRRYYYNKRT
3) VQLPVVSVTPVPAVPSRGSTVPAPSVGANTAVTRSSETTSTQDTMHFADGASAQDIEEAKKGMATAGKVNMTPVEEKVPDDEPLVY
4) WEKPLELMTPIERADASTVWKEFTTPEGRKYYHNKVTK
5) WTIPEELKLAREQAQAAASQGTPSGSGVAPQAPVATAVSAAETPTTAIPVSSNTLQDSSPVSVTPVANPSPTSVSGPTTGPVAQSAAMSAT
825
1
336
203
244
984
198
421
240
334










Molecular Recognition Features






MoRF SequenceStartStop




1) GYEELED
2) KDDREESKKSRRH
3) KEKDRKHRKRHAADD
4) RHRKHKRDHR
5) RKKSRKH
968
918
899
951
934
974
930
913
960
940