<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12981

Description mediator of RNA polymerase II transcription subunit 27-like
SequenceMLQQHHQQQQHHHHLQSAITAAPPPSATTSTPPSSTTGEAPPKQVALAMDRLGQAARLIADIRLGADRLLEALFVASQPHQSSKPLHLFRQEDESMRQHLQDLRTVGKQLEESGVLNESLRSRSNSWGLHMPLVCPDGAVVAYAWKRQLAGQAGASAVDRTRLALKAFTDQKRRFFPHLDDEEDGEGTDTASKKHRNLPALAEDNQDNLSDCKTLSDVLTNMEKEIPNLKVSTYERLDWLKRASSLPASANDNTMEAPKHNFHSTSILRPAPQNVASMDKVAVIELFFPSIFRAVVSLHPAGSTDPDSVAFFSPDEGGSYMHSRGSSVYHVFRQITEHATVALQYFLGIRSKTALHSLLHWICSYQTLFTKVCNKCGRLLAMDRQSALILPPVHRPYRTLSVSKHSSTQSISSTLDQGSNAPEAYHIGCFSDNT
Length434
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.457
Instability index54.78
Isoelectric point7.38
Molecular weight48029.51
Publications
PubMed=25893780

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12981
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     399.35|     111|     227|      24|     135|       1
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   24-  135 (183.79/120.59)	PPSATTST..PPS....STTGEAP.PKQV.....ALAMDRLGQAARLIADIR......LGADRLLEALFVASQPHQSSKPLHL.FRQEDES...MRQHLQDLRTVGKQLEESG..VLNESLRSRSNSwGLH..MPLVC
  137-  221 (77.46/44.03)	...........DG....AVVAYAW.KRQLagqagASAVDRTRLALKAFTDQKrrffphLDDEEDGEGTDTASKKHRNLPALA.......ED...NQDNLSDCKTLSDVLTN...........................
  247-  363 (138.10/84.70)	PASANDNTmeAPKhnfhSTSILRPaPQNV.....A.SMDK.......VAVIE......LFFPSIFRAV.VSLHPAGSTDPDSVaFFSPDEGgsyMHSRGSSVYHVFRQITEHAtvALQYFLGIRSKT.ALHslLHWIC
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12981 with Med27 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) FFPHLDDEEDGEGTDTASKKHRNLPALAEDNQ
2) MLQQHHQQQQHHHHLQSAITAAPPPSATTSTPPSSTTGEAPPKQVALA
175
1
206
48

Molecular Recognition Features

MoRF SequenceStartStop
NANANA