<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12975

Description LOW QUALITY PROTEIN: mediator of RNA polymerase II transcription subunit 16-like
SequenceMNQQPGLGDNKESEEEPVAQPVDSAVKLGLEKPVGSEPVSGVGEDEVFVASSGKSEDTVMEEDPVNPAIVFCIWLKQPKSNLRYKMRVPELCRNFSAVAWCGKLNAIACATETCARIPSSNANPPFWIPIQIVIPERPTECAVFNVTADSPRDSVQFIEWSPTSCPRALLIANFHGRVTIWTQPSQEPAHLVRDASFWKREHEWRQDIAVVTKWLSGVSPYRWLSSKSSNPANSKSTFEEKFLSHQSQNSARWPNFLCVCSVFSSGSVQLHWSQWPPTHGSVARKWFCTSKGILGAGPSGIMAADAIITDSGAMHVAGVPIVNPSTVVVWEVTPGTGNGFQATAKTSTSNGIPPSVNPPNWAGFAPLAAYLFSWQEYLISEAKQGKKTADQDFNDVVSLHCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRGGSVIAVVIVEGQYMSPYDPDEGPTITGWRVQRWESSLQSVVLHNIFGNPSSSFGGQAPKQTVWVSKVDTSIPPTNDFKSHQAAAAGPTSDSRKASDSSSEKLKRVSFDPFDLPSDVRTLARIVYSAHGGEIAISFLRGGVHIFSGPNFSAVDNYQINVGSAIAAPAFSSTSCCSASVWHDTSKDRTMLKIIRVLPPAISSSQIKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSIQHRQQYGPSLDRIKCRLLEGTNAQEVRAMVLDMXARLLLDMLGKGIESALVNPSALVSEPWQASGETLSSIDPEAMAVDPALVQSIQAYVDAVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNMVTSPTQSSATPATSQAGQSGTTSSTGSTQMQAWVQGAIAKISGSTDGVSTSTPNTISGPSSFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRALQPRYAQRNTDANPQKNQPGAPGKMEEVNSIAAKPTTMTRPDEAQGARAGQLVPGAKGAEEGHRTGKIGSGNAGQGYTFEEVKVLFLILMDLCRRTSGLPHPLPVSQVGSSSIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPSSEEWHRRNMFGGPWSDLEDMSPGDDIPRLSNSIDMPDTSSMESSNVHYGVQTLWPRKRRLSERDAAFGLNTSVGLGAYLGIMGSRRDVVTAVWKTGLEGVWYKCMRCLRQTSAFASADSTHQPSQNERVSWWISRWAYGCPMCGGPWVRVV
Length1248
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.08
Grand average of hydropathy-0.218
Instability index44.25
Isoelectric point6.47
Molecular weight134967.58
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12975
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.78|      17|      19|     788|     804|       1
---------------------------------------------------------------------------
  788-  804 (28.66/18.30)	IQAYVDAVLDLASHFIT
  806-  822 (30.12/19.58)	LRRYASFCRTLASHAVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.11|      14|      19|     238|     254|       2
---------------------------------------------------------------------------
  222-  235 (22.88/ 6.56)	RWLSSKSSNPANSK
  241-  254 (27.22/19.43)	KFLSHQSQNSARWP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      59.09|      12|      19|       7|      18|       3
---------------------------------------------------------------------------
    7-   18 (20.68/10.65)	LGDNKESEEEPV
   28-   39 (19.76/ 9.86)	LGLEKPVGSEPV
   54-   65 (18.65/ 8.93)	KSEDTVMEEDPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.82|      19|      21|     833|     853|       4
---------------------------------------------------------------------------
  835-  853 (33.66/20.23)	PTQSSATPATSQ...AGQSGTT
  855-  876 (29.16/10.75)	STGSTQMQAWVQgaiAKISGST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     556.52|     176|     568|     474|     673|       5
---------------------------------------------------------------------------
  474-  673 (277.26/194.03)	SSLQsVVLHNIFGNpsssfggqapkqTVWVSKVDTSIPP..TNDFKSHQAAAAGPTSDSRKASDSSSEKLKRVSF.DPF.DL....P.SDVRTLARIVYSAHGGEIAISFLRGGVHIFsGPN...FSAVD.NYQIN..VGSAIAAPAFSSTSCCSASVWHdTSKDRTMLKIIRVLPpaiSSSQIKANSSTWERAIAERF.WWsllvgVDWWdAVGC
 1045- 1237 (279.26/149.30)	SSIQ.VRLHYIDGN...........yTVLPEVVEASLGPhmQNMPRPRGADAAGLLLRELELHPSSEEWHRRNMFgGPWsDLedmsPgDDIPRLSNSIDMPDTSSMESSNVHYGVQTL.WPRkrrLSERDaAFGLNtsVGLGAYLGIMGSRRDVVTAVWK.TGLEGVWYKCMRCLR...QTSAFASADSTHQPSQNERVsWW.....ISRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.47|      20|      20|     164|     183|       6
---------------------------------------------------------------------------
  164-  183 (38.04/23.55)	SCPRALLI..ANFHGRVTIWTQ
  185-  206 (34.43/20.60)	SQEPAHLVrdASFWKREHEWRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.71|      13|      21|     332|     344|       7
---------------------------------------------------------------------------
  332-  344 (24.15/11.36)	VTPGTGNGFQATA
  356-  368 (26.56/13.26)	VNPPNWAGFAPLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.58|      17|      24|     878|     894|       9
---------------------------------------------------------------------------
  878-  894 (30.73/16.62)	GVSTSTPN.TISGPSSFM
  901-  918 (28.85/15.13)	GTFPGTPAvRLIGDCHFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.29|      10|      19|     753|     762|      11
---------------------------------------------------------------------------
  753-  762 (17.09/ 9.86)	VNPSALVSEP
  773-  782 (18.20/11.05)	IDPEAMAVDP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12975 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQRNTDANPQKNQPGAPGKMEEVNSIAAKPTTMTRPDEAQGARAGQLVPGAKGAEEGHRTGKIGSGN
2) GTGSNRNMVTSPTQSSATPATSQAGQSGTTSSTGST
940
824
1006
859










Molecular Recognition Features






MoRF SequenceStartStop




NANANA