<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12974

Description mediator of RNA polymerase II transcription subunit 33B-like isoform X3
SequenceMAVSVQAASPVWESVLEQTKSAQDKNRDPLLWAVQLSSSLNSAGISLPSIDLAHLLVSHICWDNHVPITWKFLEKALTVKFVPSMLVLALLSTRVFPNRKFHPAAYRLYMELLRRHAFSLKCQINGPNYQKIMKSVGDVLHLSQIFGVKVSEPGLLLVEFVFSIVWQLLDASLDDEGLLELTPEKRSIWPTVTQDMEIDSVDNFNEKRSEHHDVLCKGNTTMAIEIIGEFLQNKVTSRILFLARRNMPSHWGTFIQQLRVLAAKSVALRNAKHITPEALLNLTSDMHKVVSRKCKTISQQEFNAVIGSGSLTTSSGQCHGTSPSAHWLPIDLFLEDAMDGSQVAATGAVESLTGLVKALQAVNGTTWHDTFLGLWIAALRLVQRERDISEGPVPRLDTCLCMLLSITPLVVANIVEEEESELIDGSDCSPTNQIKEKQATGRCRQDLISSLQMLGDYEALLTPPQPVRSVANQAAAKAIMFVSGLTVGNGYYECMSINDMPMNCSGNMRHLIVEACISRNLLDTSAYVWPGYVNARANIPRNVPVQVTGWSSLMKGSPLTPTLINALIATPASSLAEIEKIYEIATKGSDDEKISAASILCGASLVRGWNIQVPLLAGTLMPLCEVFGSTSPNVSWTLPTGEELTSHAVFSNAFTLLLRLWRFNHPPFENAMGDATPVGSQLTPEYLLLVRNSKLSDFGKSPKDHMKLKRMSKNLNISLELLFMDSFPKLKSWYRQHQECIASTLSGLVQGTTVHQIVDALLNMMFRKISRGGQSLTSTTSGSSNSPASGAEDVSMRLKVPAWDILEGAPYVLDAALTACAHGRLLPRDLATGLKDLADLLPATLATIVSYLSAEVTRGIWKPVFMNGTDWPSPSANLFMVEQQIKKIIAATGVDVPSLAIGGSSPAMLPLPLAALVSLTITYKLDKASERFIVLIGPALSSLAESCPWPCMPIIASLWAQKVKRWSDFLVFSASRTVFHHNIDAVVQLLRSCFTLIPGLSPSTIYSNGGVGALLGHGFGSHFSGGMSAVAPGILYLRVHRSVRNIMFMTEEIVSLLMSSVRDIANSGLFRENLEKLKKAKFGLRYRQVSLGAATTQVRLAASLGASLVWLSGGLSLVQLLIQETLPSWFLSAHNPDQDGGEPGGLVAMLSGYALAYFVVLCGTLVWGVDSSSPTSKRRPKVLGAHLEFLASAIDGKISLGCEHATWHAYVTGFVSLMVGCTKKWVLDVNVDVLRRLSNGLRQWNEEELAIALLGLGGTEATASAAELIIEIGP
Length1274
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy0.153
Instability index44.90
Isoelectric point7.01
Molecular weight138674.98
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12974
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.50|      22|     118|     556|     580|       2
---------------------------------------------------------------------------
  556-  580 (32.60/24.69)	GSPLTPTLinaLIATPASSLAEIEK
  679-  700 (36.90/20.15)	GSQLTPEY...LLLVRNSKLSDFGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.37|      17|      20|      80|      96|       3
---------------------------------------------------------------------------
   80-   96 (28.89/18.43)	KFVPS..MLVLALLSTRVF
  100-  118 (27.49/17.18)	KFHPAayRLYMELLRRHAF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.07|      12|     675|     529|     554|       4
---------------------------------------------------------------------------
  529-  554 (18.79/33.64)	WPGYVnaraniprnvpvqvTGWSSLM
 1207- 1218 (26.28/12.65)	WHAYV..............TGFVSLM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.51|      13|      20|     144|     156|      10
---------------------------------------------------------------------------
  144-  156 (21.89/14.81)	QIFGVKVSEPGLL
  167-  179 (20.62/13.44)	QLLDASLDDEGLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12974 with Med33 domain of Kingdom Viridiplantae
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