<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12971

Description heat shock cognate 70 kDa protein-like
SequenceMAAKAEGKAIGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPSNTVFDAKRLIGRRFTDPSVQSDMKHWPFKVVAGPGDKPMIVVTYKGEEKQFAAEEISSMVLTKMKEVAEAYLGQTVKNAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDKKGSKSGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRLVNHFVQEFKRKHKKDISSNARALRRLRTACERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLKDSKLDKSRVNEVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGDDKVQDLLLLDVTPLSLGIETAGGVMTVLIPRNTTIPTKKEQIFSTYADNQPGVLIQVYEGERARTNDNNLLGKFELTGIPPAPRGVPQINVCFDIDANGILNVSAEDKTAGVKNKITITNDKGRLSKEEIERMVQEAERYKAEDEQVKKKVEAKNALENYAYNMRNTIKDDKVAGKLDPSDKGKMEKAIDETIEWLDRNQLAEVDELEDKLNELEGLCNSIIAKMYQGGGDDVPMGGARTGSGGSGAGPKVEEVD
Length646
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.422
Instability index30.79
Isoelectric point5.22
Molecular weight70757.32
Publications
PubMed=25893780

Function

Annotated function
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central
GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12971
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.82|      19|      74|     448|     466|       1
---------------------------------------------------------------------------
  448-  466 (32.63/19.81)	VYEGERARTNDNNLLGKFE
  525-  543 (28.19/16.17)	VQEAERYKAEDEQVKKKVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.28|      18|      21|      38|      55|       4
---------------------------------------------------------------------------
   16-   33 (18.88/ 9.54)	....TTYSCVGVWQNDRveIIA
   38-   55 (33.04/21.61)	NR..TTPSYVAFTDTER..LIG
   60-   78 (25.37/15.07)	NQvaMNPSNTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.09|      10|      74|     512|     522|       6
---------------------------------------------------------------------------
  512-  522 (12.80/ 9.79)	DKGRLSKeEIE
  572-  581 (16.29/ 7.72)	DKGKMEK.AID
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12971 with Med37 domain of Kingdom Viridiplantae

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