<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12969

Description luminal-binding protein 5-like
SequenceMAGSWRARGSLVVLAIVLFGCLFAISIAKEEATKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDSERLIGEAAKNQAAVNAERTIFDVKRLIGRKFDDKEVQKDMKLVPYKIVNRDGKPYIQVKIKDGETKVFSPEEISAMVLTKMKETAEAFLGKKIKDAVVTVPAYFNDAQRQATKDAGIIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDHRVMDYFIKLIKKKHGKDISKDNKALGKLRREAERAKRALSSQHQVRVEIESLFDGIDFSEPLTRARFEELNNDLFRKTMGPVKKAMEDAGLEKRQIDEIVLVGGSTRIPKVQQLLKDYFDGKEPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSMTKDGRWLGRFDLTGIPPAPRGTPQIEVTFEVDANGILNVKAEDKGTGKSEKITITNDKGRLSQEEIERMVREAEEFAEEDKKLKEKIDARNSLETYVYNMKNQISDKDKLADKLESDEKEKVETAVKEALEWLDDNQNAEKEDFEEKLKEVEAVCNPIITAVYQRSGGGPGGAASNEEEDDSHDEL
Length667
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.451
Instability index28.58
Isoelectric point5.17
Molecular weight73586.53
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12969
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     100.53|      27|      27|     563|     589|       1
---------------------------------------------------------------------------
  531-  562 (22.24/10.11)	...EKI..TITNdkgrlsqeEIERMVREAEEFAEEDK
  563-  589 (43.14/25.71)	KLKEKI..DARN........SLETYVYNMKNQISDKD
  590-  618 (35.16/19.76)	KLADKLesDEKE........KVETAVKEALEWLDDNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.32|      14|      32|     101|     114|       3
---------------------------------------------------------------------------
   78-   91 (20.97/10.94)	DSERLIGEAAKNQA
  101-  114 (23.72/13.28)	DVKRLIGRKFDDKE
  130-  143 (23.64/13.21)	DGKPYIQVKIKDGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     242.90|      76|     104|     343|     419|       4
---------------------------------------------------------------------------
  343-  419 (122.92/79.32)	RKTMGPVKKAMEDAGLEKRQID.EIVLVGGSTRIPKVQQLLKDY.FDGKEPNKGVNPDEAVAYGAAVQgGILSGEGGDE
  448-  525 (119.98/72.75)	RNTVIPTKKSQVFTTYQDQQTTvSIQVFEGERSMTKDGRWLGRFdLTGIPPAPRGTPQIEVTFEVDAN.GILNVKAEDK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12969 with Med37 domain of Kingdom Viridiplantae
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