<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12967

Description U-box domain-containing protein 33-like
SequenceMDQMTDTAETIYVAVGKAVEESKHTLLWALQNLCPTKVCILHVHQPASLFNSSRMNFTASRLHQQEIGKKILDRIMNDYLLICGQKSVEAAKLNIEMDDAGKGIVELIRDQSIKKLVMGAAADKHFSEGMTDLKSEKAQYVELHAPPSCKIWFICGGQLVHRRPLVENGQSNLSSSASSSSYWTGSNKVASSSDPSVSGTLGESPDWLEFNEGSGDDKVFENLEQALFTAEKSNQEAFEKLDRLLKAEKDALNAVVSQANEMKSSYIGELRRRKEIEAMLRKQNEELEQVTQQRDQARKIARTHKLLLESRGAKSDHVKVLEAKLSSAMEQLQICQRERDDLRTKLERTCNSIEDHSTKQEEGSSNVHMQQFFSEFSVAEIHDAPEDFDPSFKIAEGAYGSVYRSTLRHTEVAIKVLHQNSLQGPLEFQKEVDILSKLRHPNLVTLIGVCPEIWALINEYLPNGSLEDRLSPRDSTPPLSWQTRIHIATEICSALIFLHSSKPQRIVHGNLKPGNILLDTNFGCKLSDFGVCHVLSSLENSNNMTDIGRKFPYLDPQFFNTRTLTPSSDIYSFGIILLQLITGRPPLSIIEDVQHAVNGKRLNDLLDPSAGDWSYVEAEQLTRWALRCCDTNRSRRPDLASEVYKVLEPIRNTIGPLSTFHAGSGELRQPPDSFFCPISKEIMTDPHVAADGFTYELRQIRRWLDGGHNTSPCTNIPLAHRNLIPNHALRTAILEW
Length736
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.430
Instability index44.58
Isoelectric point6.00
Molecular weight82733.77
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12967
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     186.48|      45|      50|     511|     556|       2
---------------------------------------------------------------------------
  462-  503 (54.54/32.32)	..PNGSLED.....RLSPRDSTP.PLSWQTRIHIATEICSAL.IFLhssKP
  511-  556 (73.99/50.83)	LKPGNILLDtNFGCKLSDFGVCH.VLSSLENSNNMTDIGRKF.PYL...DP
  564-  608 (57.95/34.79)	LTPSSDIY..SFGIILLQLITGRpPLSIIEDVQHAVN.GKRLnDLL...DP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.23|      35|      48|     263|     303|       4
---------------------------------------------------------------------------
  263-  298 (36.71/34.72)	...............KSSYIgelrrrKEIEAMLRKQNEELEQVTQQRDQAR
  299-  343 (47.21/29.41)	KIARThklllesrgaKSDHV......KVLEAKLSSAMEQLQICQRERDDLR
  345-  371 (31.30/17.15)	KLERT....................cNSIEDHSTKQEEGSSNVHMQQ....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.61|      13|     424|      23|      35|       6
---------------------------------------------------------------------------
   23-   35 (26.71/18.13)	KHTLLWALQNLCP
  439-  451 (24.90/16.43)	RHPNLVTLIGVCP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12967 with Med32 domain of Kingdom Viridiplantae

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