<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12966

Description mediator of RNA polymerase II transcription subunit 33B-like isoform X2
SequenceMAVSVQAASPVWESVLEQTKSAQDKNRDPLLWAVQLSSSLNSAGISLPSIDLAHLLVSHICWDNHVPITWKFLEKALTVKFVPSMLVLALLSTRIMKSVGDVLHLSQIFGVKVSEPGLLLVEFVFSIVWQLLDASLDDEGLLELTPEKRSIWPTVTQDMEIDSVDNFNEKRSEHHDVLCKGNTTMAIEIIGEFLQNKVTSRILFLARRNMPSHWGTFIQQLRVLAAKSVALRNAKHITPEALLNLTSDMHKVVSRKCKTISQQEFNAVIGSGSLTTSSGQCHGTSPSAHWLPIDLFLEDAMDGSQVAATGAVESLTGLVKALQAVNGTTWHDTFLGLWIAALRLVQRERDISEGPVPRLDTCLCMLLSITPLVVANIVEEEESELIDGSDCSPTNQIKEKQATGRCRQDLISSLQMLGDYEALLTPPQPVRSVANQAAAKAIMFVSGLTVGNGYYECMSINDMPMNCSGNMRHLIVEACISRNLLDTSAYVWPGYVNARANIPRNVPVQVTGWSSLMKGSPLTPTLINALIATPASSLAEIEKIYEIATKGSDDEKISAASILCGASLVRGWNIQEHTILFITSLLSPPVPADYSGNESHLISYGPFFNILLVGISPVDCVQIFSLHGLVPLLAGTLMPLCEVFGSTSPNVSWTLPTGEELTSHAVFSNAFTLLLRLWRFNHPPFENAMGDATPVGSQLTPEYLLLVRNSKLSDFGKSPKDHMKLKRMSKNLNISLELLFMDSFPKLKSWYRQHQECIASTLSGLVQGTTVHQIVDALLNMMFRKISRGGQSLTSTTSGSSNSPASGAEDVSMRLKVPAWDILEGAPYVLDAALTACAHGRLLPRDLATGLKDLADLLPATLATIVSYLSAEVTRGIWKPVFMNGTDWPSPSANLFMVEQQIKKIIAATGVDVPSLAIGGSSPAMLPLPLAALVSLTITYKLDKASERFIVLIGPALSSLAESCPWPCMPIIASLWAQKVKRWSDFLVFSASRTVFHHNIDAVVQLLRSCFTLIPGLSPSTIYSNGGVGALLGHGFGSHFSGGMSAVAPGILYLRVHRSVRNIMFMTEEIVSLLMSSVRDIANSGLFRENLEKLKKAKFGLRYRQVSLGAATTQVRLAASLGASLVWLSGGLSLVQLLIQETLPSWFLSAHNPDQDGGEPGGLVAMLSGYALAYFVVLCGTLVWGVDSSSPTSKRRPKVLGAHLEFLASAIDGKISLGCEHATWHAYVTGFVSLMVGCTKKWVLDVNVDVLRRLSNGLRQWNEEELAIALLGLGGTEATASAAELIIEIGP
Length1291
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy0.199
Instability index45.39
Isoelectric point6.25
Molecular weight140036.43
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12966
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     300.97|      97|     173|    1010|    1111|       1
---------------------------------------------------------------------------
 1010- 1111 (153.44/130.50)	CFTLIPGL...SPSTIYSNGGVGALLgHGFGSHFSGGMSAvapGILYLRVHRSVRN.IMFM...TEE.IVSLLMSSVRDIANsGLFRENLEKLKKAKFGLRYRQVSLGAA
 1179- 1283 (147.53/107.30)	CGTLVWGVdssSPTSKRRPKVLGAHL.EFLASAIDGKISL...GCEHATWHAYVTGfVSLMvgcTKKwVLDVNVDVLRRLSN.GLRQWNEEELAIALLGLGGTEATASAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.62|      12|      15|     557|     568|       2
---------------------------------------------------------------------------
  557-  568 (19.96/11.02)	ISAASILCGASL
  574-  585 (20.66/11.65)	IQEHTILFITSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.16|      11|      15|     631|     644|       5
---------------------------------------------------------------------------
  631-  642 (16.63/13.77)	PLLAGTLmPLCE
  649-  659 (22.53/ 6.64)	PNVSWTL.PTGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.46|      30|     173|     586|     616|       7
---------------------------------------------------------------------------
  424-  453 (48.14/33.84)	LTPPQPVRSVANQAAAKAI.MFVSGLTVGNG
  459-  475 (21.89/10.26)	SINDMPMNCSGNMRHLI..............
  586-  616 (49.43/40.83)	LSPPVPADYSGNESHLISYgPFFNILLVGIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.23|      23|     460|     342|     364|       8
---------------------------------------------------------------------------
  342-  364 (41.66/26.00)	LRLVQRERDISEGPVPRLDTCL..C
  813-  837 (35.57/21.08)	MRLKVPAWDILEGAPYVLDAALtaC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.91|      28|     599|     283|     315|      11
---------------------------------------------------------------------------
  283-  315 (44.01/38.00)	GT...SPSAhwlpiDLFLEDAMDGSQVAATGA.VESL
  885-  916 (40.90/22.59)	GTdwpSPSA.....NLFMVEQQIKKIIAATGVdVPSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.05|      11|      16|     701|     711|      13
---------------------------------------------------------------------------
  701-  711 (19.30/13.77)	P.EYLLLVRNSK
  719-  730 (16.75/10.89)	PkDHMKLKRMSK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12966 with Med33 domain of Kingdom Viridiplantae
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