<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12965

Description mediator of RNA polymerase II transcription subunit 33B-like isoform X1
SequenceMAVSVQAASPVWESVLEQTKSAQDKNRDPLLWAVQLSSSLNSAGISLPSIDLAHLLVSHICWDNHVPITWKFLEKALTVKFVPSMLVLALLSTRVFPNRKFHPAAYRLYMELLRRHAFSLKCQINGPNYQKIMKSVGDVLHLSQIFGVKVSEPGLLLVEFVFSIVWQLLDASLDDEGLLELTPEKRSIWPTVTQDMEIDSVDNFNEKRSEHHDVLCKGNTTMAIEIIGEFLQNKVTSRILFLARRNMPSHWGTFIQQLRVLAAKSVALRNAKHITPEALLNLTSDMHKVVSRKCKTISQQEFNAVIGSGSLTTSSGQCHGTSPSAHWLPIDLFLEDAMDGSQVAATGAVESLTGLVKALQAVNGTTWHDTFLGLWIAALRLVQRERDISEGPVPRLDTCLCMLLSITPLVVANIVEEEESELIDGSDCSPTNQIKEKQATGRCRQDLISSLQMLGDYEALLTPPQPVRSVANQAAAKAIMFVSGLTVGNGYYECMSINDMPMNCSGNMRHLIVEACISRNLLDTSAYVWPGYVNARANIPRNVPVQVTGWSSLMKGSPLTPTLINALIATPASSLAEIEKIYEIATKGSDDEKISAASILCGASLVRGWNIQEHTILFITSLLSPPVPADYSGNESHLISYGPFFNILLVGISPVDCVQIFSLHGLVPLLAGTLMPLCEVFGSTSPNVSWTLPTGEELTSHAVFSNAFTLLLRLWRFNHPPFENAMGDATPVGSQLTPEYLLLVRNSKLSDFGKSPKDHMKLKRMSKNLNISLELLFMDSFPKLKSWYRQHQECIASTLSGLVQGTTVHQIVDALLNMMFRKISRGGQSLTSTTSGSSNSPASGAEDVSMRLKVPAWDILEGAPYVLDAALTACAHGRLLPRDLATGLKDLADLLPATLATIVSYLSAEVTRGIWKPVFMNGTDWPSPSANLFMVEQQIKKIIAATGVDVPSLAIGGSSPAMLPLPLAALVSLTITYKLDKASERFIVLIGPALSSLAESCPWPCMPIIASLWAQKVKRWSDFLVFSASRTVFHHNIDAVVQLLRSCFTLIPGLSPSTIYSNGGVGALLGHGFGSHFSGGMSAVAPGILYLRVHRSVRNIMFMTEEIVSLLMSSVRDIANSGLFRENLEKLKKAKFGLRYRQVSLGAATTQVRLAASLGASLVWLSGGLSLVQLLIQETLPSWFLSAHNPDQDGGEPGGLVAMLSGYALAYFVVLCGTLVWGVDSSSPTSKRRPKVLGAHLEFLASAIDGKISLGCEHATWHAYVTGFVSLMVGCTKKWVLDVNVDVLRRLSNGLRQWNEEELAIALLGLGGTEATASAAELIIEIGP
Length1328
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy0.174
Instability index45.30
Isoelectric point6.64
Molecular weight144526.66
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12965
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     300.97|      97|     171|    1047|    1148|       1
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 1047- 1148 (153.44/113.43)	CFTLIPGL...SPSTIYSNGGVGALLgHGFGSHFSGGMSAvapGILYLRVHRSVRN.IMFM...TEE.IVSLLMSSVRDIANsGLFRENLEKLKKAKFGLRYRQVSLGAA
 1216- 1320 (147.53/93.25)	CGTLVWGVdssSPTSKRRPKVLGAHL.EFLASAIDGKISL...GCEHATWHAYVTGfVSLMvgcTKKwVLDVNVDVLRRLSN.GLRQWNEEELAIALLGLGGTEATASAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.73|      11|      20|      86|      96|       2
---------------------------------------------------------------------------
   86-   96 (16.90/11.28)	LVLALLSTRVF
  108-  118 (19.83/14.77)	LYMELLRRHAF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.62|      12|      15|     594|     605|       3
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  594-  605 (19.96/11.54)	ISAASILCGASL
  611-  622 (20.66/12.20)	IQEHTILFITSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.32|      43|     171|     456|     504|       4
---------------------------------------------------------------------------
  461-  504 (75.71/66.47)	LTPPQPVRSVANQAAAKAI.MFVSGLTVGNGYYECMSIND............MPMnC
  623-  678 (67.61/42.13)	LSPPVPADYSGNESHLISYgPFFNILLVGISPVDCVQIFSlhglvpllagtlMPL.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.23|      23|     468|     379|     401|       7
---------------------------------------------------------------------------
  379-  401 (41.66/25.51)	LRLVQRERDISEGPVPRLDTCL..C
  850-  874 (35.57/20.67)	MRLKVPAWDILEGAPYVLDAALtaC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.65|      27|     171|     119|     159|      10
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  125-  158 (37.46/41.43)	NGPNYQKIMksvGDVLHLsqifGVKVSEPGLLLV
  718-  744 (50.19/19.15)	NHPPFENAM...GDATPV....GSQLTPEYLLLV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12965 with Med33 domain of Kingdom Viridiplantae
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