<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12963

Description mediator of RNA polymerase II transcription subunit 25-like isoform X2
SequenceMAEKQLIVAVEGTAAMGPYWHIVVSDYLDKIIRCFCSSELTGQKNSTSNVEFSLVTFNTHGSYCACLVQRSGWTKDVDIFLQWLSAIPFSGGGFNDAAIAEGLSEALMMFPIASNGNQTPQNVDGQRHCILVAASNPYPLPTPVYRPQIQNLEQVENSEAQTESRLSDAETVARSFAQCSVSLSVICPKQLAKLKAIYSAGKQNPRAADPPVDNVKNSQFLVLISENFMEGRAALSRSGLPSLATNQSPVKMDMASVTSVTGPPPSSVNGSMVGRLPVSVGNVATATVKVEPTTITSMATGPAFSHVPSVPRAPSQAIPTLQTSSPLTNTLEGMTSGDNMQELKPSVSGMTQPSRPVPPAAANVNILNNLSQARVMSSAALTGGTSIGLQSMVQTPVAMHMSNMISSGMASSVPPAHTVLSSGQPTMTSLTGSGALTGAAQVLPNSGLSSFSSATSNVAGNSNIGISQPMGNVQGAVNIGQSVPGMSQGNHSGTQMMQSGVGMSQNMSALGQSTVSSGNGTMIPTPGMSQQVQSGMQALGVSNSSAASMPLSQQTSSALQSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASETLAAHWPQTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLGQLQEKKLCAVIQLPQQTLLLSVSDKACRLIGMLFPGDMVVFKPQMSSQQQLQLQQQQMQPQLQQQQQQQNPQLQQQQLPHLQQQQLPQLQQQQQQQQLPQLQQQQLSQLQQQQQQQKQQQQQQQQSQHPQMQQQQLSQQQQMVGSGMGPAYVQGPG
Length799
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.04
Grand average of hydropathy-0.313
Instability index61.61
Isoelectric point8.64
Molecular weight85354.64
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12963
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     151.47|      25|      25|     703|     727|       1
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  481-  510 (34.06/ 7.21)	QSV..PGMSQGNHS.GT..QMMQsgvgmsQNMSAL
  703-  724 (42.76/10.78)	.....PQLQQQQQQ.QN.PQLQQ......QQLPHL
  725-  749 (34.94/ 7.57)	QQQqlPQLQQQQQQ.QQlPQLQQ......QQL...
  757-  780 (39.70/ 9.53)	QQQ..KQQQQQQQQsQH.PQMQQ......QQLS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.81|      21|      52|     629|     650|       2
---------------------------------------------------------------------------
  629-  650 (32.39/20.77)	DFLVFRA.MNQHGFLgQLQEKKL
  680-  701 (33.42/16.47)	DMVVFKPqMSSQQQL.QLQQQQM
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     305.42|      51|      52|     210|     260|       3
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  210-  260 (84.85/42.10)	PPVDNV..............KNS.QFLVLISENFMEGRAALSR.......S...GLPSLATNQSPVKMDMASVTSV
  263-  298 (54.24/24.28)	PPPSSV..............NGS...........MVGRLPVS.............VGNVAT..ATVKVEPTTITSM
  302-  350 (47.40/20.30)	PAFSHVpsvprapsqaiptlQTS.SPLT....NTLEGMT...........S...G.....DNMQELK...PSVSGM
  359-  406 (60.24/27.78)	PAAANV..................NILNNLSQARVMSSAALTG.......GtsiGLQSMV..QTPVAMHMSNMIS.
  414-  466 (58.69/26.87)	PPAHTV..............LSSgQP....TMTSLTGSGALTGaaqvlpnS...GLSSFSSATSNVAGN.SNI.GI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.42|      35|      53|     512|     554|       4
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  512-  554 (53.88/35.44)	QST......VSSGNgtmiptpgMSQQVQS.........GMQALGVSNSSAASMPLSQQ
  560-  609 (51.54/20.96)	QSAqskyvkVWEGN........LSGQRQGqpvfitrleGYRSASASETLAAHWPQTMQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12963 with Med25 domain of Kingdom Viridiplantae
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