<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12956

Description heat shock 70 kDa protein-like
SequenceMAAKAEGKAIGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPSNTVFDAKRLIGRRFTDPSVQSDMKHWPFKVIAGPGDKPMIVVTYKGEEKQFAAEEISSMVLIKMKEVAEAYLGQSVKNAVITVPAYFNDSQRQATKDAGAISGLNVLRIINEPTAAAIAYGLDKKASRSGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGGDFDNRLVNHFVQEFKRKHKKDISSNARALRRLRTACERAKRTLSSTAQTTIEIDSLFEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDSKLDKSQVNEVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGDDKVQDLLLLDVTPLSLGIETAGGVMTVLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELTGIPPAPRGVPQINVCFDIDANGILNVSAEDKTAGVKNKITITNDKGRLSKEEIERMVQEAERYKAEDEQVKKKVEAKNALENYAYNMRNTIKDDKVGGKLDPSDKGKMEKAIDETIEWLDRNQLAEVDELEDKLKELEGLCNPIIAKMYQGGGGGGDVPMGGAEAGSGGSAAGPKIEEVD
Length648
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.400
Instability index34.21
Isoelectric point5.27
Molecular weight70806.48
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12956
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.26|      38|      58|     512|     568|       1
---------------------------------------------------------------------------
  512-  550 (56.00/64.69)	DKGRLSKeEIERMVQEAERYK.AEDEQVKKKVEAKNALEN
  572-  610 (59.27/28.70)	DKGKMEK.AIDETIEWLDRNQlAEVDELEDKLKELEGLCN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.06|      11|      21|      42|      53|       2
---------------------------------------------------------------------------
   42-   53 (16.57/13.00)	PSYVAFtDTERL
   66-   76 (20.49/11.21)	PSNTVF.DAKRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.82|      51|      59|     389|     444|       4
---------------------------------------------------------------------------
  389-  444 (77.17/67.88)	EGD.DKVQDLLLLDVTPLSlGIETAG.GVMTVliprNTTIPTKKEQIFS.TYSDNQPGV
  450-  503 (75.65/51.66)	EGErARTKDNNLLGKFELT.GIPPAPrGVPQI....NVCFDIDANGILNvSAEDKTAGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.28|      15|     411|     207|     221|       6
---------------------------------------------------------------------------
  207-  221 (27.38/15.28)	GGGTFDVSLLTIEEG
  620-  634 (29.90/17.35)	GGGGGDVPMGGAEAG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12956 with Med37 domain of Kingdom Viridiplantae
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