<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12955

Description ATP-dependent DNA helicase Q-like 4A isoform X2
SequenceMCTNFLFSLEGQKPQGTMFARLTSRQIQNSQIFQHTQVEKAWQILSSLPASCRTYLKPGTSAPVKTSTDEISHNRRGRSTLVEPSGMKWSEHMHVHPNISETDGKVNGFGRCMTSSFPSNNANTMESGNNLRGNSGITTSMFSHSNSKVSGGSLKNQTFHGVQQEQSAEVLASEIDDDDLLKDIDVDQIVSEHYQSTCTPQPSVSKFPPITPSVDKNAFAGQETCLPPELCSNCSHGCKLGHCPEAASHVQEMKDMLIAVSNELLDNATNLSSEQIEKLRQDRLQLNKQIQQLEKYISDVERQKSNFSASTATLSFQYGTPQTTSLRPNPIQFDTQVHSRNEPNGYDNWNSPTVPFSSVNSFGVPSGPIEREPYIPQIIDVNYIEGSNDQKWSSRDFPWTRKLEANNKKVFGNHSFRPNQREVINATMSGYDVFVLMPTGGGKSLTYQLPALICPGITLVISPLVSLIQDQIMHLLQANIPAAYLSANIDWSEQQEILRELTSDYCKYKLLYVTPEKVARSDVLLRHLNILNSRDLLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPKTPVLALTATATASVKEDVVQALGLINCIIFRQSFNRPNLWYSVIPKTKKCVEDIDKFIKENHFDECGIIYCLSRMDCEKVSEKLQEYGHKAAFYHGNMDPAQRAFIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCLLYYSYSDYIRVKHMISQGAAEQSPLITGHSRFNNSGRILETNTENLLRMVSYCENDVDCRRLLQLLHFGEKFDSTHCQKTCDNCCKTRSSVDKDVTNIAKQLVELVKLTGQQFSSSHILEVYRGSLSQFVKKHRHETLSLHGVGKHLAKGEASRIIHHLVVEEYLLEDVKKSDIYGSVSSVLKVNESQVKNLFSGRQAIIIRFPSTVKVGKLSKPEVTPAKGSLTTSGKLSPPRVDTPAQSQSIVDLNLSAKLYSALRMLRTILVKEAGEGVMAYHIFGNATLQHISKRVPRTKEELLEINGIGKAKILKYGDRLLETIEATIKEHYKTDKINSGSSNDSNDSAKRRRNTNANIDNNDDFSRSTGRSKRRTVERQDKDGNSDNNHQYPADENDLDFDDLDYVYDVESKENRPQVEVNINGRMLPSWPRT
Length1165
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.538
Instability index48.50
Isoelectric point7.88
Molecular weight130972.30
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12955
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     218.38|      70|     157|     841|     916|       1
---------------------------------------------------------------------------
  841-  916 (111.36/83.89)	LVKLTGQQFSSSHIL.EVYRGSLSQFVKKHRHETLSLHGVGKHLAKGEASRIIHHL...VVEEYlledvkKSDIYGSVSS
 1000- 1073 (107.02/69.23)	LVKEAGEGVMAYHIFgNATLQHISKRVPRTKEELLEINGIGKAKILKYGDRLLETIeatIKEHY......KTDKINSGSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     133.03|      31|     156|     192|     222|       2
---------------------------------------------------------------------------
  192-  222 (56.97/28.46)	EHYQ........................STC.......TPQPSVSKFP.PI...TPSVDKNAFAGQ
  282-  346 (27.26/10.20)	DRLQlnkqiqqlekyisdverqksnfsaSTAtlsfqygTPQTTSLRPN.PIqfdTQVHSRNEPNGY
  347-  377 (48.79/23.44)	DNWN........................SPT.......VPFSSVNSFGvPS...GP.IEREPYIPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.17|      15|     134|     404|     419|       4
---------------------------------------------------------------------------
  404-  419 (24.58/18.18)	EANNKKVFGnHSFRPN
  544-  558 (32.59/19.54)	EAHCVSQWG.HDFRPD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12955 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DLDYVYDVESKENRPQVEVNINGRMLPSWPRT
2) HYKTDKINSGSSNDSNDSAKRRRNTNANIDNNDDFSRSTGRSKRRTVERQDKDGNSDNNHQYPADENDLDF
3) LKPGTSAPVKTSTDEISHNRRGRSTLVEPSGMKWSEHMHVHPNISETDGKVNGFGRCMTSSFPSNNANTMESGNNLRGNSGITTSMFSHSNSKVSGGSLKNQTFHGVQQEQSAEVLASEIDD
1134
1062
56
1165
1132
177










Molecular Recognition Features






MoRF SequenceStartStop




NANANA