<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12952

Description pre-mRNA-processing protein 40C-like isoform X1
SequenceMQPPLPVPQGALSSSASFSFTPNPQLVQNAQIQPSKSDTLATGTQAMTASSPSTVSQSGPLPVNSSSGFTMNASTTRSFAPVTSRIPTTPPFPMSSGSSGTSGAPGHPGSVPSIQMITASAAVDSPSSAVPGPGAPVSLNPAVQQQVYPPYTSLPSMVSSPQGYWMQHPPLGGFPRPPFVPYPTVYPGPFPSTSSGMPLPAPSSDSQPPGVRPLGMSPFAPSAAALANQSLAIQTGFPPQGIDNRKLGHDVSTRVESAVNEQSDVWTAHKTDTGVVYYYNALTGESSYEKPAGFKGEPDQVTVQPTPVSVEQLAGTDWALVTTNDGKKYYYNSKTKISSWQIPNEVTELRKKQDSEVSKENAVPVPNIDVVAEKGSTPISLSAPAVNTGGRDAMPLRTSVVPGSSSALDLIKKKLQDPGVPSSSPVPVMPVTATHELNGSRAVDVKGLQSESNKDKLKDANGDGSISDSSSDSEDADSGPSKEECIMQFKEMLKERGVAPFSKWEKELPKIVFDPRFKAIPSHSARRSLFEHYVKTRAEEERKEKRAAQKAAIEGFRQLLDEASEDIDHDTNYQTFKRQWGSDPRFEALDRKDRGLLLNERVLLLKRAAEEKARVIRAAAASSFKSMLKEKGDINVNSRWSRVKDSLRDDPRYKCVKHEDREVLFDEYISELKAIEEKAERKDKVKKEEEEKLKERERELRKRKEREEQEMERVRLKVRRKEAVASFQALLVETIKDSQASWTESKPKLEKDPQGRAVNPDLDSSDMEKLFREHIKMLFERCVNDFRALLAEVITQDAAAQETEGGKTALNSWSTAKRLLKPDPRYNKMPRKEREALWRRYAEDMLRKQKLALDQEEEKHTDVKGRSSGGDFGRYSSGTRRTHERR
Length886
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.757
Instability index56.31
Isoelectric point8.77
Molecular weight97707.53
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
RNA polymerase binding	GO:0070063	IBA:GO_Central
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12952
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     282.90|      50|      58|       4|      53|       1
---------------------------------------------------------------------------
    4-   53 (80.42/38.86)	PLPV.......................PQG...ALSSSASFSFTPNPQLVQNAQIQPSKSDTLAT.GTQAMTASSPS
   60-  113 (71.24/33.55)	PLPV.......................NSSsgfTMNASTTRSFAPVTSRIPTTPPFPMSSGSSGTsGAPGHPGSVPS
  134-  203 (72.14/34.07)	GAPVslnpavqqqvyppytslpsmvssPQG...YWMQHPPLGGFPRPPFVPYPTVYPGPFPSTSS.G...MPLPAPS
  209-  253 (59.10/26.52)	PGVR.......................PLG...MSPFAPSAAALANQSLAIQTGFPPQGIDNRKL.GHDVST.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     262.83|      44|      58|     707|     750|       2
---------------------------------------------------------------------------
  485-  551 (42.23/19.16)	CIMQFKEMLKERG.V..APFS...........KWEKELPKIVfdprfkaipshsarrslfehyvkTRAEE.............E...RKEK.........RAAQKA
  552-  619 (38.96/17.15)	AIEGFRQLLDEAS.EdiDHDT...........NYQTFKRQWG.......................SDPRFealdrkdrglllnE...RVLLlkraaeekaRVIRAA
  620-  659 (51.71/24.99)	AASSFKSMLKEKG.D.iNVNS...........RWSRVKDSLR.......................DDP.....................RY.........KCVKHE
  660-  705 (33.49/13.79)	...DREVLFDEYI.S..ELKA.........ieEKAERKDKVK....................keeEEKLK.............E...RERE.........LRKRKE
  723-  781 (47.14/22.18)	AVASFQALLVETI.K..DSQA...........SWTESKPKLE...........kdpqgravnpdlDSSDM.............EklfREHI.........KMLFER
  782-  833 (49.31/23.51)	CVNDFRALLAEVItQ..DAAAqeteggktalnSWSTAKRLLK.......................PDPRY.............N................KMPRKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     184.46|      45|      50|     266|     312|       3
---------------------------------------------------------------------------
  266-  310 (82.42/44.08)	WTAHKTDTGVVYYYNALTGESSYEKPAGF....KGEPDQVTVQ...PTP.VSV
  318-  370 (61.36/31.67)	WALVTTNDGKKYYYNSKTKISSWQIPNEVtelrKKQDSEVSKEnavPVPnIDV
  372-  400 (40.68/19.21)	..AEKGSTPI...........SLSAPAVN....TGGRDAM......PLR.TSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.67|      14|      15|     447|     461|       4
---------------------------------------------------------------------------
  447-  461 (19.78/15.58)	GLQSESNKDKlKDAN
  464-  477 (23.88/13.95)	GSISDSSSDS.EDAD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12952 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FPSTSSGMPLPAPSSDSQPPGVRPLGMSPF
2) IPNEVTELRKKQDSEVSKENAVPVPNIDVVAEKGSTPISLSAPAVNTGGRDAMPLRTSVVP
3) IQTGFPPQGIDNRKLGHDVSTRVESAVNEQSDVW
4) LIKKKLQDPGVPSSSPVPVMPVTATHELNGSRAVDVKGLQSESNKDKLKDANGDGSISDSSSDSEDADSGPSKEECIMQF
5) MQPPLPVPQGALSSSASFSFTPNPQLVQNAQIQPSKSDTLATGTQAMTASSPSTVSQSGPLPVNSSSGFTMNASTTRSFAPVTSRIPTTPPFPMSSGSSGTSGAPGHPGSVPSIQMITASAAVDSPSSAVPGPGAPVSLNPAVQQQ
6) QKLALDQEEEKHTDVKGRSSGGDFGRYSSGTRRTHERR
190
342
233
410
1
849
219
402
266
489
146
886










Molecular Recognition Features






MoRF SequenceStartStop




1) ALWRRYA
2) FGRYSS
3) LDLIKKKLQ
836
872
408
842
877
416