<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12945

Description U-box domain-containing protein 52-like isoform X1
SequenceMAPRLSPDDNLPADSTAVAIDKDKNSPHAVRWAIDHLVISNPIIVLIHVRHRNQGEPESDYDINQLFVPFRGYCARKGIQAREVVLEDVDISKALIDYVSRNLINSIVLGAATRGAISSYLSYRKFKSDIPTTLIKTAPDFCSVYVISKGKILTVRTAQRPVSNTAAPPKAPVGMPPQIPSDQSEDDGYRGQYTRGVPGNAGSERLSFDNSSRAPIRDRHRSSPGNMSLDIDVVRGPSSSRQDSLSSDIDFPAKISLGSVDISGQNLDLSSSNSESSSQSARDIEDEMRRLKLELKQTMDMYSSACKEALTAKKTANELHQWKMEESRRFEEARQAGEAALAMAEMEKAKCRAAIEAAEAAQKLAEMEAYRRRQAESKAKKESDEKNRALNALATNDVRYRKYSIVEIEEATENFSASNKIGEGGYGPVYKGKLDHTPVAIKILRPDAAQGKKQFQQEVEVLCSIRHPHMVLLLGACPEYGCLVYEYMHNGSLEDRLFRKGNTHPLSWRRRFKIAAEIATALLFLHQAKPEPLVHRDLKPANILLDRNYVSKISDVGLARLVPPSVADSVTQYHMTSAAGTFCYIDPEYQQTGMLTTKSDIYSLGIMLLQIITAKPPMGLAHHVGRAIEKGTLADLLDPAVPNWPMEEALSFAQLALQCAELRKRDRPDLATVILPELNRLRDLGYNNNGSSSSGYSQGHGGSDQSQGFNTSGCSRGHSGSDGLCSPFSRSRVSSSSSQESLSKSANSEPGSMLNLKLDRAE
Length762
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.484
Instability index47.94
Isoelectric point7.90
Molecular weight83824.68
Publications
PubMed=25893780

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12945
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.25|      20|      20|     335|     354|       1
---------------------------------------------------------------------------
  335-  354 (35.00/24.93)	QAGEAALAMAEMEKAKCRAA
  356-  375 (34.25/24.24)	EAAEAAQKLAEMEAYRRRQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     111.00|      20|      20|     213|     232|       2
---------------------------------------------------------------------------
  213-  232 (37.49/18.88)	RAPIRDRHR.......SSPGNM.SLDID
  235-  250 (28.47/12.68)	RGPSSSRQD.......S....L.SSDID
  716-  729 (24.64/10.05)	RG.....HS.......GSDG.L.CSPFS
  732-  759 (20.40/ 7.13)	RVSSSSSQEslsksanSEPGSMlNLKLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.07|      14|      21|     174|     187|       3
---------------------------------------------------------------------------
  174-  187 (27.58/17.28)	GMPPQIPSDQ.SEDD
  196-  210 (21.49/11.75)	GVPGNAGSERlSFDN
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12945 with Med32 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AQRPVSNTAAPPKAPVGMPPQIPSDQSEDDGYRGQYTRGVPGNAGSERLSFDNSSRAPIRDRHRSSPGNMSLDIDVVRGPSSSRQDSLSSDID
2) ISGQNLDLSSSNSESSSQSARDIEDEMRRLKL
3) YNNNGSSSSGYSQGHGGSDQSQGFNTSGCSR
158
262
686
250
293
716

Molecular Recognition Features

MoRF SequenceStartStop
1) MLNLKLDRAE
2) PFSRSRV
753
727
762
733