<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12944

Description U-box domain-containing protein 52-like isoform X2
SequenceMAPRLSPDDNLPADSTAVAIDKDKNSPHAVRWAIDHLVISNPIIVLIHVRHRNQGEPESDYDINQLFVPFRGYCARKGIQAREVVLEDVDISKALIDYVSRNLINSIVLGAATRGAISRKFKSDIPTTLIKTAPDFCSVYVISKGKILTVRTAQRPVSNTAAPPKAPVGMPPQIPSDQSEDDGYRGQYTRGVPGNAGSERLSFDNSSRAPIRDRHRSSPGNMSLDIDVVRGPSSSRQDSLSSDIDFPAKISLGSVDISGQNLDLSSSNSESSSQSARDIEDEMRRLKLELKQTMDMYSSACKEALTAKKTANELHQWKMEESRRFEEARQAGEAALAMAEMEKAKCRAAIEAAEAAQKLAEMEAYRRRQAESKAKKESDEKNRALNALATNDVRYRKYSIVEIEEATENFSASNKIGEGGYGPVYKGKLDHTPVAIKILRPDAAQGKKQFQQEVEVLCSIRHPHMVLLLGACPEYGCLVYEYMHNGSLEDRLFRKGNTHPLSWRRRFKIAAEIATALLFLHQAKPEPLVHRDLKPANILLDRNYVSKISDVGLARLVPPSVADSVTQYHMTSAAGTFCYIDPEYQQTGMLTTKSDIYSLGIMLLQIITAKPPMGLAHHVGRAIEKGTLADLLDPAVPNWPMEEALSFAQLALQCAELRKRDRPDLATVILPELNRLRDLGYNNNGSSSSGYSQGHGGSDQSQGFNTSGCSRGHSGSDGLCSPFSRSRVSSSSSQESLSKSANSEPGSMLNLKLDRAE
Length757
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.486
Instability index48.41
Isoelectric point7.91
Molecular weight83211.03
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12944
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     111.00|      20|      20|     208|     227|       1
---------------------------------------------------------------------------
  208-  227 (37.49/23.24)	RAPIRDRHR.......SSPGNM.SLDID
  230-  245 (28.47/15.68)	RGPSSSRQD.......S....L.SSDID
  711-  724 (24.64/12.47)	RG.....HS.......GSDG.L.CSPFS
  727-  754 (20.40/ 8.92)	RVSSSSSQEslsksanSEPGSMlNLKLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.25|      20|      20|     330|     349|       2
---------------------------------------------------------------------------
  330-  349 (35.00/22.54)	QAGEAALAMAEMEKAKCRAA
  351-  370 (34.25/21.91)	EAAEAAQKLAEMEAYRRRQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     303.74|     103|     443|      80|     203|       4
---------------------------------------------------------------------------
   80-  203 (143.60/137.13)	QAR..EVVLEDVDISKALID..YVSRnlINSIVLG...................AATRGAISRKFKSdipTTLIKTAPDFCSVYVISKgKILTvrtaqrpvsntAAPpkaPVGMPPQIpSDQSEDDGYRGQYTRGVPGNAGSERLSF
  522-  647 (160.14/99.74)	QAKpePLVHRDLKPANILLDrnYVSK..ISDVGLArlvppsvadsvtqyhmtsaAGTFCYIDPEYQQ...TGMLTTKSDIYSLGIMLL.QIIT...........AKP...PMGLAHHV.GRAIEKGTLADLLDPAVPNWPMEEALSF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12944 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQRPVSNTAAPPKAPVGMPPQIPSDQSEDDGYRGQYTRGVPGNAGSERLSFDNSSRAPIRDRHRSSPGNMSLDIDVVRGPSSSRQDSLSSDID
2) ISGQNLDLSSSNSESSSQSARDIEDEMRRLKL
3) YNNNGSSSSGYSQGHGGSDQSQGFNTSGCSR
153
257
681
245
288
711










Molecular Recognition Features






MoRF SequenceStartStop




1) MLNLKLDRAE
2) PFSRSRV
748
722
757
728