<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12940

Description mediator of RNA polymerase II transcription subunit 33B-like isoform X2
SequenceMAVSVQAASPVWESVLELTKSAQDKNRDPLLWAVQLSSSLNSAGISLPSIDLAHLLVSHICWDNHVPITWKFLEKALTVKFVPSMLVLALLSTRVIPNRKFHPAAYRLYMELLRRHAFSLQCQINGPNYQKSSHWGTFLQQLRVLAAKSVALRNAKHITPEALLNLTSDMHKVVSRKCKTISQQELNAVIGSGSLTTSSGQCHGTSPSAHWLPIDLFLEDAMDGSQVAATGAVESLTGLVKALQAVNGTTWHDTFLGLWIAALRLVQRERDISEGPVPRLDTCLCMLLSITPLVVANIVEEEESELIDGCDCSPTNQIKEKQSPGRCRQDLISSLQMLGDYEALLTPPQPVRSVANQAAAKAIMFVSGLTVGNGYYECMSINDMPMNCSGNMRHLIVEACIARNLLDTSAYVWPGYVNARANIPRNVPVQVIGWSSLMKGSPLTPTLINALIATPASSLAEIEKIYEIATKGSDDEKISAASILCGASLVRGWNIQEHTILFITSLLSPPVPADYSGSESHLISYGPFFNILLVGISPVDCVQIFSLHGLVPLLAGTLMPLCEVFGSTSPNVSWTLPTGEELTSHAVFSNAFTLLLRLWRFNHPPFENAMGDATPVGSQLTPEYLLLVRNSKLSDFGKSPKDHMKLKRMSKNLNISLELIFMDSFPKLKSWYRQHQECIASTLTGLVQGTTVHQIVDALLNMMFRKISRGGQSLTSTTSGSSSSPASGAEDVSMRLKVPAWDILEGAPYVLDAALTACAHGRLLPRDLATGLKDLADLLPATLATIVSYLSAEVTRGIWKPVFMNGTDWPSPSANLFMVEEQIKKIIAATGVDIPSLAIGGSSPAMLPLPLAALVSLTITYKLDKASERFIVLIGPALSSLAESCPWPCMPIIASLWAQKVKRWSDFLVFSASRTVFHHNIDAVVQLLRSCFTSIPGLSPSTIYSNGGVGALLGHGFGSHFSGGMSAVAPGILYLRVHRSVRNIMFMTEEIVSLLMSSVRDIANSGLFRENLEKLKKAKFGLRYRQVSLGAATTRVRFAASLGASLVWLSGGLSLVQLLIQETLPSWFLSAHTPDQDGGEPGGLVAMLSGYALAYFVVLCGTLAWGVDSSSPTSKRRPKVLGAHLEFLASAIDGKISLGCEYATWHAYVTGFVSLMVGCTKKWVLDVNVDVLRRLSNGLRQWNEEELAIALLGLGGAEATASAAELIIEIGP
Length1212
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy0.205
Instability index46.51
Isoelectric point7.33
Molecular weight131240.57
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12940
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     205.84|      74|     173|     931|    1032|       1
---------------------------------------------------------------------------
   81-  121 (38.99/ 8.53)	............................................FVPSMLVLALLST.RVIPNRKFhpaaYRLYMELLRRHAFSLQ
  180-  220 (55.18/21.41)	TI.SQQELNAVIGSGSLTTSSGQCHGTSPSAHWLPID......LFLED......................................
  942- 1023 (111.67/116.71)	TIySNGGVGALLGHGFGSHFSGGMSAVAPGILYLRVHrsvrniMFMTEEIVSLLMSSvRDIANSGL....FRENLEKLKKAKFGLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     287.16|      91|     173|     440|     537|       2
---------------------------------------------------------------------------
  440-  537 (136.68/115.95)	GSPLTPTLINALIATPASSLAEIEKIYEIATKGSDDEKISAASILCGA.SLVRGWNIQEHTilFITSLLSPPVpadySGSESHLIsYGPFFNILLVGIS
  617-  708 (150.48/104.98)	GSQLTPEYLLLVRNSKLSDFGKSPKDHMKLKRMSKNLNISLELIFMDSfPKLKSWYRQHQE..CIASTLTGLV....QGTTVHQI.VDALLNMMFRKIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.24|      23|     468|     263|     285|       3
---------------------------------------------------------------------------
  263-  285 (41.66/24.09)	LRLVQRERDISEGPVPRLDTCL..C
  734-  758 (35.58/19.54)	MRLKVPAWDILEGAPYVLDAALtaC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.91|      28|      67|     759|     788|       8
---------------------------------------------------------------------------
  759-  788 (39.31/32.31)	AHGRLLPrDLATGLKDLAdLLPATLATIVS
  829-  856 (49.60/30.44)	ATGVDIP.SLAIGGSSPA.MLPLPLAALVS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12940 with Med33 domain of Kingdom Viridiplantae
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