<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12934

Description U-box domain-containing protein 35-like isoform X1
SequenceMEKKEREEAENELVLPPSPTLTIGIAINGNRESKYVVKWALEKFVPEGNVMFKLLHVRAKIKLVPTPMGNLLPISQVREDVAAAYKKELEWQANEMLLPYKMCAQRKVEADIIIIESDQVANAIAEEVSKNTITRLVIGASSRGMLTRKLKKNNLSSRISACAPSFCTVYAISKGKLTSIRPSDSEMNGSTKDDSSETSFSSKNSSDYSFSSLTELGSVATYATFRSPSLPMQRSQTLSMINQTHLHSRTSSLASNQFRSTESTQFKSPDNNHSRCQSLDNAAGNDDMSSCPNSSESREAVSRNSSRRSLQTYQQSWLPDQISTLDAQADNNPSECEVNINFELEKLRTELRHIREMHAAAQSETIDASQKLNTLSKRRLEEAMKLKEVCLKEEEAKELARQEKAKCEAAIREAVHVKGCADREASLRREAAMKASHEAKEKEKLENYLTGPLQQYQKFTWDEIVSATSSFSEDLRIGMGAYGTVYKCIFHHTAAAVKVLHSKENGRTKQFQQELEILSKIRHPHLLLLLGACPEHGCLVYEYMENGSLEDRLLRKNNTPPIPWFERYRIAWEVGSALVFLHNSKPEPIIHRDLKPANILLDHNFMSKIGDVGLSVMITTDSSSTSTVYKDTGPVGTLCYIDPEHQRTGLISPKSDIYAFGMIILQLLIAKPAIALTHVVETAIDNDNLTRILDSEAGNWPVEETKELAILGLSCAELRRKDRPGLKDRVLPILEKMKEVANKARNSISNIQSAHPNHFICPISKDVMDEPCVAADGYTYERKAIEKWIETNDISPMTNLALPNKNLLPNYSLLSAILEWKSRKQ
Length825
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.474
Instability index48.34
Isoelectric point7.06
Molecular weight92557.35
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12934
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     167.48|      41|      43|     225|     265|       1
---------------------------------------------------------------------------
  168-  204 (37.23/20.32)	..TVYAISKGKLTSiRPSDS...EMNG.....STKDDS.................sETSFSSKN
  205-  234 (47.79/28.28)	SSDYSFSSLTELGS..VATY...A...............T.............FR.SPSLPMQR
  235-  270 (55.39/34.00)	SQTLSMINQTHLHS.RTSSL...ASNQ.....FRSTESTQ.............FK.SPD.....
  271-  322 (27.07/12.66)	.......NN...HS.RCQSLdnaAGNDdmsscPNSSESREavsrnssrrslqtYQ.QSWLPDQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.07|      14|      80|       3|      16|       2
---------------------------------------------------------------------------
    3-   16 (24.26/16.49)	KKEREEAENELVLP
   86-   99 (26.81/19.04)	KKELEWQANEMLLP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12934 with Med32 domain of Kingdom Viridiplantae

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