<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12933

Description U-box domain-containing protein 33-like isoform X3
SequenceMDRMTDAAETIYVAVGKAVEESEHTLLWALQNLCPTKVCILHVHQPASLCNSSRMNFTATRLHQQDIGKKILDRIMDDYLLICGQKSVEAAKLNIEMDDAGKGIVELIRDQGIKKLVMGAAANKHFSEGMTDLKSEKAQYVELHAPPSCKIWFICGGQLVHRKSLVENGQSNLSSSASSSSYWTVSNKLASSSDSSVSETLGESPDWLEFNEGSGDDKVFENLEQALFIAEKSNQEAFDELDRRLKAEKDALNAVVRQANEMKSSYIGELRRRKEIEGTLRKQNEELEQVKQQRDEARKIARTHKLLLESRGAKSDHVKVLEAKVSSAMEQLQIYQRERDDLRAKLESTCMSIKDHSTIQEEGSSNVHMQQFFSEFSVAEIHDATEDFDPSFKIAEGAYGSVYRCTLRHTEVAIKVLHQNSLQGPLEFQKEVDILSKLRHPNLVTLIGVCPEIWALIYEYLPNGSLEDRLIPRDNTPPLSWQTRIQIATEICSALIFLHASKPQRMVHGNLKPGNILLDTNFGCKLSDFGVCHVLSSLEKSNNMTDISRKFPYLEPQFLNTRTLTPSSDIYSFGIILLQLITGRPPLSIIEDAQRAVNGNRLNDLLDPSAGDWSYVEAEQLTHLALRCCDTNRSRRPDLASEVYKVLIRNTIGPLSTIHAGSEQLRQPPDSFFCPISKKIMMDPHVAADGFTYELREIRRWLDGGHDTSPCTNIPLAHRILIPNHALRSAILEW
Length734
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.387
Instability index42.87
Isoelectric point5.93
Molecular weight82632.98
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP12933
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.45|      15|     248|     201|     218|       1
---------------------------------------------------------------------------
  180-  196 (21.61/10.78)	SSYWTVSNklASSSDSS
  204-  218 (28.84/12.66)	SPDWLEFN..EGSGDDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     195.38|      61|      87|     504|     590|       3
---------------------------------------------------------------------------
  504-  571 (95.70/96.46)	QRMVHGNLKpgNILLDTNFGcklsDFGVCHV..LSSLEKSNNMTDISRKfPYLEP...QFLNTRTLTPSSDIY
  594-  659 (99.68/49.92)	QRAVNGNRL..NDLLDPSAG....DWSYVEAeqLTHLALRCCDTNRSRR.PDLASevyKVLIRNTIGPLSTIH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.36|      11|      15|     370|     380|       6
---------------------------------------------------------------------------
  370-  380 (19.42/13.59)	QQFFSEFSVAE
  386-  396 (19.94/14.16)	EDFDPSFKIAE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP12933 with Med32 domain of Kingdom Viridiplantae

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