<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12914

Description mediator of RNA polymerase II transcription subunit 17-like isoform X1
SequenceMDGNLEISLDKLPVKRLDAIEENGLERYPPESSYDEKRVSLIRRIDFAWAVEEDEEKERKKKQKKNSSKDASATWQWQSMVENLQLAHQELSVIIDLINTVEANDAVTVAGMTRPKPLPNELMSGLAVSAATKLQCYWHLGKYFKQSANALEQQIAREARFYGALIRLQQNWKVKRQRVAGPGPASSNEGFTIDLFDNSLYSSTLMSRPSSLSSICVEHDSAGMLSINLPPNSCHSLHFGFLDVHSADIPKEFNKIRTHGSVGQHTRNTEKESMSDDEYVKETHLLLRDVHQSIFNDQVFDMLNCEAFNQSVGVNVTGMRENYLQLSIGQGTSLFISLVPSSESNNQAVDTANTQNVDSAIVALDSFDEVKFGEREHDTPTMKKKWGFPHRISCEIYLQQIVHEHAFLKAKDKPNLSGTPVSGQSGKDGPGLLGHFCLSLAHRIFSSRVLIELENVVCRVPYLHLMTHPTWHSRTSSWTIFMKVPQSILHAESQSPRSDFQNIKDVIKSQFHTKVVLSDDRINVEGEGAPNVAGLFKRSSEDICSVNKYDCDLVDLPVILLQQVASQVIRWLHEEALMVGIKTNRDFLSLTFDLEQGESVSLVAHVDPEDIQGGISWWLVMEYGFAEDWKLQMEMYDGTPEYRKFLGHLNLDVLYSTMMDLVTLCDGGGNQ
Length671
PositionHead
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.08
Grand average of hydropathy-0.372
Instability index44.05
Isoelectric point5.47
Molecular weight75650.63
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12914
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     220.53|      75|     239|      31|     110|       1
---------------------------------------------------------------------------
   31-  110 (113.67/105.13)	ES.SYDE..KRVSLIRRiDFAWAVEEDEEKERKKKQKKNSSKDASATwqwqSMVEN.LQLA.HQELSVIIDLINTVEAND.AVTVA
  272-  352 (106.86/80.58)	ESmSDDEyvKETHLLLR.DVHQSIFNDQVFDMLNCEAFNQSVGVNVT....GMRENyLQLSiGQGTSLFISLVPSSESNNqAVDTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.31|      52|     217|     389|     453|       2
---------------------------------------------------------------------------
  389-  453 (70.30/73.79)	PHRISCEIYlQQIVHEHAFlkAKD.KPNL...SGTPvsgQSGKdgpgLLGHFCLSLahrIFSSRV.LIEL
  608-  664 (84.02/49.44)	PEDIQGGIS.WWLVMEYGF..AEDwKLQMemyDGTP...EYRK....FLGHLNLDV...LYSTMMdLVTL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12914 with Med17 domain of Kingdom Viridiplantae
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