<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12912

Description mediator of RNA polymerase II transcription subunit 15a-like isoform X2
SequenceMDYRDCEKETCRETTDHDQETLMNGNNLKPTSASEKPAMGRGDWRTQLRSDLRERIIVNKMFDTLKRHLRSSGEDKLNELRKTVEAFEEKTYNAASNQFDYVRRISLKLLQKETQSQNIVQNSGQCSNNLHNPGSQSMQSEQVHGEGLSHQNIPNDMKGKVNIYDLPGKDGPDVIFPKQWPPLPALYISEQTPTIRSTSVDCADLTMAQQNNHSNMHQQQQQQQQLMAQQNNLSNMHQQQLGPQSNISGLQQQQQQLVGTQSGNSSMQTNQQSLHMLSQPKVALQQTQQTAPNLLPTQGQTSQQPQQQQQLMSQMQSQPTQLRQQLGLQQQPNQVQQNMQQRLQASGQTSSSLLQSQNLIDQQQQLYQSQRAVPETSSTSLDSTAQTGHSNGGDWQEEVYQKIKAMKETYFPELNMMHEKISATLLQVEHDSLPQQTKSARLEKMKLFKTMLERILSFLTISRAAIVPAFKDKLSSYEDQIGKFIIANRPRKLVSALQQGQLLPTHMHSMQQPQPESNQTQSHDNQMNPLFPSMMRPAQMPQLKKQMPRLQQLQLLQMLQQRGMHRVDELQSPAKIKTNELSYLHQIDIDSGVLQENLPSNQLPGYEQASSEYHAPDTAGIGVPPIMSIPPLLPGFKEVNDTSGNALTTDFGKPDIAEQPHDLKAKPKSLSATVVTMVDEAVTSVGEDLAAMRKQGLHARNFFTQTGMSGAEKMRCYLSALVILALIIFFIFNLNHQY
Length738
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.05
Grand average of hydropathy-0.783
Instability index59.89
Isoelectric point6.88
Molecular weight83390.07
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12912
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     174.27|      28|      29|     213|     240|       1
---------------------------------------------------------------------------
  222-  252 (42.78/12.36)	QQQQLMAQQNNLSNMHQQQ.....lgpQ......SN.ISGLQQ
  253-  289 (31.20/ 7.23)	QQQQLVGTQSGNSSMQTNQ.....qslHmlsqpkVA.LQQTQQ
  290-  320 (35.32/ 9.05)	TAPNLLPTQGQTSQQPQQQ.....qqlM......SQ.MQSQPT
  362-  397 (30.98/ 7.13)	QQQQLYQSQRAVPETSSTSldstaqtgH......SN.GGDWQE
  498-  525 (33.98/ 8.46)	QQGQLLPTH..MHSMQQPQ.......pE......SNqTQSHDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.96|      23|      25|     448|     470|       2
---------------------------------------------------------------------------
  448-  470 (36.64/31.37)	FKTMLERILSFLTISRA.AIVPAF
  474-  497 (32.33/26.74)	LSSYEDQIGKFIIANRPrKLVSAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.28|      28|      29|     603|     630|       3
---------------------------------------------------------------------------
  603-  630 (51.74/34.97)	LPGYEQASSEYHAPDTAGIGVPPIMSIP
  633-  660 (49.54/33.17)	LPGFKEVNDTSGNALTTDFGKPDIAEQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.31|      29|     204|     125|     153|       5
---------------------------------------------------------------------------
  125-  153 (53.09/27.46)	QCSNNLHNPGSQSMQ.SEQVHGEGLSHQNI
  330-  359 (45.22/22.18)	QQPNQVQQNMQQRLQaSGQTSSSLLQSQNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      78.68|      15|     105|     433|     447|       6
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  433-  446 (17.58/ 6.77)	...LPQQTKSARLEKMK
  530-  541 (21.31/ 9.92)	L..FPSMMRPA...QMP
  542-  554 (21.14/ 9.78)	Q..LKKQM..PRLQQLQ
  555-  571 (18.65/ 7.68)	LlqMLQQRGMHRVDELQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12912 with Med15 domain of Kingdom Viridiplantae
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