<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12903

Description mediator of RNA polymerase II transcription subunit 17-like isoform X5
SequenceMDGNLEISLDKLPVKRLDAIEENGLERYPPESSYDEKRVSLIRRIDFAWAVEEDEEKERKKKQKKNSSKDASATWQWQSMVENLQLAHQELSVIIDLINTHLGKYFKQSANALEQQIAREARFYGALIRTHGSVGQHTRNTEKESMSDDEYVKETHLLLRDVHQSIFNDQVFDMLNCEAFNQSVGVNVTGMRENYLQLSIGQGTSLFISLVPSSESNNQAVDTANTQNVDSAIVALDSFDEVKFGEREHDTPTMKKKWGFPHRISCEIYLQQIVHEHAFLKAKDKPNLSGTPVSGQSGKDGPGLLGHFCLSLAHRIFSSRVLIELENVVCRVPYLHLMTHPTWHSRTSSWTIFMKVPQSILHAESQSPRSDFQNIKDVIKSQFHTKVVLSDDRINVEGEGAPNVAGLFKRSSEDICSVNKYDCDLVDLPVILLQQVASQVIRWLHEEALMVGIKTNRDFLSLTFDLEQGESVSLVAHVDPEDIQGGISWWLVMEYGFAEDWKLQMEMYDGTPEYRKFLGHLNLDVLYSTMMDLVTLCDGGGNQ
Length543
PositionHead
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.08
Grand average of hydropathy-0.413
Instability index43.11
Isoelectric point5.29
Molecular weight61721.93
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12903
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.31|      52|     217|     261|     325|       1
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  261-  325 (70.30/86.94)	PHRISCEIYlQQIVHEHAFlkAKD.KPNL...SGTPvsgQSGKdgpgLLGHFCLSLahrIFSSRV.LIEL
  480-  536 (84.02/58.34)	PEDIQGGIS.WWLVMEYGF..AEDwKLQMemyDGTP...EYRK....FLGHLNLDV...LYSTMMdLVTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.32|      30|     215|     159|     191|       2
---------------------------------------------------------------------------
  159-  191 (50.06/45.12)	LRDVHQSIFNDQVF...DMLNCEAFNQSvgvNVTGM
  375-  407 (46.26/32.75)	IKDVIKSQFHTKVVlsdDRINVEGEGAP...NVAGL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12903 with Med17 domain of Kingdom Viridiplantae
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