<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12899
Description |
Mediator of RNA polymerase II transcription subunit 9 |
Sequence | MDPYLGGSWTMIPSIPTQSNVSTPTNQDHLYLSPPPPSQQQQFHPQQFQQQQQQRLLQQQQQQQQQQQQQVQQNQQQQSLASHFHLLHLVENLADAIDNGSRDQHSDALVNELNNHFEKCQQLLNSIAASINSKSMTVEGQKKKLEESEQLLNQRRDLIAKYRSSVEDLLKTEP |
Length | 174 |
Position | Middle |
Organism | Gossypium hirsutum (Upland cotton) (Gossypium mexicanum) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -1.073 |
Instability index | 63.93 |
Isoelectric point | 5.74 |
Molecular weight | 20072.90 |
Publications | PubMed=25893780
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364145
|
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP12899
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.81| 17| 23| 39| 56| 1
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39- 56 (31.95/13.51) QQQQfHPQQFQQ.QQQQRL
63- 80 (29.86/ 8.74) QQQQ.QQQQVQQnQQQQSL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 54.37| 16| 26| 110| 125| 2
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110- 125 (28.83/17.36) VNELNNHFEKCQQLLN
138- 153 (25.54/14.70) VEGQKKKLEESEQLLN
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