<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12898

Description mediator of RNA polymerase II transcription subunit 36a
SequenceMRPPRGRGGGGFRGRGDGGRGRGRGGGGRGGDRGGSAMKSRGGGRGGGRGGGRGRGGMKGGSKVIVEPHRHEGVFVAKGKEDALVTKNMVPGEAVYNEKRIAVQNEDGTKIEYRVWNPFRSKLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDVVGPTGVVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKAGGHFVISIKANCIDSTVPAEAVFQSEVKKLQQEQFKPFEQVTLEPFERDHACVVGGYRMPKKQKAAT
Length302
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.414
Instability index34.09
Isoelectric point10.20
Molecular weight32221.50
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
box C/D RNP complex	GO:0031428	IBA:GO_Central
Cajal body	GO:0015030	IBA:GO_Central
small-subunit processome	GO:0032040	IBA:GO_Central

GO - Biological Function
histone-glutamine methyltransferase activity	GO:1990259	IBA:GO_Central
RNA binding	GO:0003723	IBA:GO_Central
rRNA methyltransferase activity	GO:0008649	IBA:GO_Central

GO - Biological Process
box C/D RNA 3'-end processing	GO:0000494	IBA:GO_Central
histone glutamine methylation	GO:1990258	IBA:GO_Central
rRNA methylation	GO:0031167	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12898
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.63|      14|      24|      20|      36|       2
---------------------------------------------------------------------------
   20-   36 (26.87/10.70)	RGRGrggGGRGGDRGGS
   39-   52 (30.77/ 7.83)	KSRG...GGRGGGRGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.36|      14|      16|      53|      66|       3
---------------------------------------------------------------------------
   53-   66 (24.84/12.23)	RGRGGM..KGGSKVIV
   70-   85 (19.52/ 8.09)	RHEGVFvaKGKEDALV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.14|      40|     159|      90|     130|       4
---------------------------------------------------------------------------
   90-  130 (65.65/45.46)	VPGEAVYNEKRIAVQNEDGTKIEYRVWNPFRSKlAAAILGG
  252-  291 (70.50/44.70)	VPAEAVFQSEVKKLQQEQFKPFEQVTLEPFERD.HACVVGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.03|      17|      17|     183|     199|       5
---------------------------------------------------------------------------
  163-  186 (20.30/12.63)	TGVVYAVEfshrsgrDLVNMAKKR
  187-  203 (30.72/22.54)	TNVIPIIE.......DARHPAKYR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12898 with Med36 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MRPPRGRGGGGFRGRGDGGRGRGRGGGGRGGDRGGSAMKSRGGGRGGGRGGGRGRGGMKGGSKVIVEPHRHE
1
72










Molecular Recognition Features






MoRF SequenceStartStop




1) MRPPRGRGGGGFRGRGDGGRGRGRGGGGRGGDRGGSAMKSRGGGRG
1
46