<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12884

Description pre-mRNA-processing protein 40A-like
SequenceMDPSQNFPPPMSGQFRPVVPSQQPQQFVSVPPQQFQPVGRGVTVMNAGFPSQTPQPQIPQVMQQLPARPGQPGHILPPPPSVSLPAAQPNLHVNPGASVPQPNIQAPNNYFPGVPASHLSSSYTFAPSSYGQVTVSHNAMAQYQPMAQLQAPNVPVGGQVGIHVSQSTSVTSAQQIGEQPSASTATIPPKPTEEALTDWIEHTSANGRRYYYNKKTRQSSWEKPLELMTPIERADASTNWKEYTSPDGRKYYYNKVTNLSTWSLPEELKLAREQVEMVSAKGPLSEVSSHIPAPVPPASKAQSGADTPSTIIQGASSSPVPVAPVPSSSKIESVVVSGSDLPVATSSTVTNVDVVQIVEDTITPSVAVSESSEVSLSVADAATTLMNNISKVSSLDMVSSEGVSTQNADETVKDVVVSEKINNALEEKAIDQESLTYASKQEAKDAFKALLESANVGSDWTWDQAMRVIINDKRYGALRTLGERKQAFNEFLGQKKKQDAEERRIKQKKAREEYKKMLEECLELTSSTRWSKAVTMFENDERYKAVEREKDRKDFFENYIDELRQKVFFVPLTLIYFSWCVSKMYITL
Length588
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.506
Instability index59.81
Isoelectric point5.72
Molecular weight64590.81
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12884
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.32|      39|      40|     189|     227|       2
---------------------------------------------------------------------------
  189-  227 (76.75/50.80)	PKPTEEALTDWIEHTSANGRRYYYNKKTRQSSWEKPLEL
  230-  268 (76.57/50.66)	PIERADASTNWKEYTSPDGRKYYYNKVTNLSTWSLPEEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.39|      15|      16|      44|      59|       3
---------------------------------------------------------------------------
   31-   49 (19.66/ 8.75)	PPQQFQPvgrGVT.VMNaGF
   50-   65 (24.73/ 8.67)	PSQTPQP...QIPqVMQ.QL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.24|      15|      16|      81|      96|       4
---------------------------------------------------------------------------
   81-   96 (24.40/14.22)	SVSLPAAQ.PNLHVnPG
   98-  113 (26.85/11.74)	SVPQPNIQaPNNYF.PG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      64.06|      18|      18|     318|     335|       5
---------------------------------------------------------------------------
  289-  302 (20.48/ 8.62)	.........SHIP.APVPPASKAQ
  309-  332 (24.87/12.25)	STIiqgassSPVPVAPVPSSSKIE
  333-  350 (18.71/ 7.16)	SVV...vsgSDLPVA...TSSTVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.60|      33|      33|     386|     418|       6
---------------------------------------------------------------------------
  386-  418 (51.78/41.51)	MNNISKVSSLDMVSSEGVSTQNADETVKDVVVS
  421-  453 (50.82/40.59)	INNALEEKAIDQESLTYASKQEAKDAFKALLES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.98|      18|      18|     150|     167|       7
---------------------------------------------------------------------------
  125-  138 (25.70/11.83)	FAPS..SYGQVT..VSHN
  150-  167 (33.53/17.54)	QAPNVPVGGQVGIHVSQS
  169-  183 (18.76/ 6.76)	...SVTSAQQIGEQPSAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.62|      23|      66|     455|     477|       9
---------------------------------------------------------------------------
  455-  477 (43.89/35.29)	NVGSDWTWDQAMRVIINDKRYGA
  523-  545 (40.73/32.17)	ELTSSTRWSKAVTMFENDERYKA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12884 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQYQPMAQLQAPNVPVGGQVGIHVSQSTSVTSAQQIGEQPSASTATIPPKPTEEALTDWI
2) KGPLSEVSSHIPAPVPPASKAQSGADTPSTIIQGASSSP
3) MDPSQNFPPPMSGQFRPVVPSQQPQQFVSVPPQQFQPVGRGVTVMNAGFPSQTPQPQIPQVMQQLPARPGQPGHILPPPPSVSLPAAQPNLHVNPGASVPQPNIQAPNNYFPG
141
281
1
200
319
113










Molecular Recognition Features






MoRF SequenceStartStop




NANANA