<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12881

Description U-box domain-containing protein 34-like isoform X4
SequenceMDENVVAMYVQEVKLKFGQVFIPFLNLFKTSKVETVVLEDDYPAVGLLRYISEFGIQTLVLGSYSSNYMKRKLKGPGVPNSVLKCAPDTCDIRVVYRQRIITKQGTSSSGIKKHIYGPINASAESTAQNSFGTASSFELNYPYLHAFSSRGSLTNASSISHCHSLGSTQSEKLNLQAEVEQLRLELQNTVAMYKEACEELVDTQNKVRLLSSECLEEASRVNAAQEREEAFRKIAAEEKVKLLQAMKDVEEAKHLLSREANRRQMAELNAHKESLEKQKFVDALFCCDRRYRKYTRDEIEVATDFFSVSNVIGQGGYGKVYKCSLHRTPVAVKVLQSDALDRKEEFLREVEVLSQLHHPHIVLLLGACPENGCLVYEYLENGSLEEHILQKSGKPPLPWFIRFRIVFEVASGLAFLHNSKPDPIVHRDLKPGNILLDRNYVSKIGDVGLAKLISDVVPDNITMYKDSILAGTLFYMDPEYQRTGTVRPKSDLYALGLTTLQLVTARHPNGLLLAVENAIKNCCLADILDKSITDWPLAETEELARIALKCSKLRCRDRPDLDTEVLPILKRLVDVADASLKLGKNNVYAPSYYFCPILQEVMDDPHIAADGFTYEHRAIKAWLGKHNVSPVTKRQLQHSVLTPNHTLRSAIHDWKSRVTLSST
Length663
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.08
Grand average of hydropathy-0.260
Instability index43.28
Isoelectric point7.56
Molecular weight74648.77
Publications
PubMed=25893780

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12881
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.99|      31|      32|     190|     220|       1
---------------------------------------------------------------------------
  162-  196 (42.69/24.57)	CHSLGSTQSEKLNLQAEVeqlrLELQNTVAMYKEA
  197-  227 (50.29/30.06)	CEELVDTQNKVRLLSSEC....LEEASRVNAAQER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.24|      35|     562|      10|      86|       2
---------------------------------------------------------------------------
   21-   55 (62.22/99.69)	FIPF.........LNLFKTSKVETVVLEDDYPAVGLL..RYISEFG
  400-  445 (52.03/13.34)	FIRFrivfevasgLAFLHNSKPDPIVHRDLKPGNILLdrNYVSKIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.49|      26|     562|      61|      86|       4
---------------------------------------------------------------------------
   61-   86 (47.58/28.26)	LGSYS.SNYMKRKLKGPGV.PNSVLKCA
  623-  650 (37.92/21.22)	LGKHNvSPVTKRQLQHSVLtPNHTLRSA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12881 with Med32 domain of Kingdom Viridiplantae
Unable to open file!