<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12876

Description mediator of RNA polymerase II transcription subunit 15a-like isoform X1
SequenceMDTNNWMSTPPSGEPTMDTGDWRTQLLPVSRQRIVNKVMDTLKRHLPFSGQEGLNELRKIAVRFEEKIFTAATSQSDYLKRISLKMLTMENRSQSTVPKTRNKSIPPDPGSQGMQNQVHSQGQPIPISLQSNQSQAQLLPQSVPNNMASAGVQSSAGLQSGMPDVSGLTLNPVPDVVEQHE
Length181
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.03
Grand average of hydropathy-0.664
Instability index67.17
Isoelectric point8.07
Molecular weight19933.29
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12876
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.49|      16|      17|     129|     145|       1
---------------------------------------------------------------------------
  112-  127 (28.48/10.07)	QGMQNQVHSQGQPIPI
  130-  145 (29.02/14.17)	QSNQSQAQLLPQSVPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.98|      10|      16|      27|      36|       3
---------------------------------------------------------------------------
   27-   36 (17.96/10.84)	LPVSRQRIVN
   46-   55 (19.02/11.86)	LPFSGQEGLN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12876 with Med15 domain of Kingdom Viridiplantae
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