<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12872

Description ATP-dependent DNA helicase
SequenceMPDQNDSVESQKCYDKLPNVNWLRHFDAHDKFACQNKFLCTNFLFSLEGQKPQGTMFARLTSRQIQNSQIFQHTQVEKAWQILSSLPASCRTYLKPGTSAPVKTSTDEISHNRRGRSTLVELSGMKRSEHMHVHPNSSETESKVNGFGRCMTSSFPSNNANTMESGNNLRGNSGITTSMFSHSNSKVSGGSLKNQTFHGVQQEQSADVLANEIDDDDLLKLLNLGFILMQSIGHIDCIKDIDVDQIVSEHYQSTCTPQPSVSKFLPITPSVDKNAFAGQETCLPPELCSNCSHGCKLGHCPEAASHVQEMKDMLIAVSNELLDNATNLSLEQIEKLRQDRLQLNKLIQQLEKYLSDVERQKSNFSASTATLSFQYGTPQTTSLRTNPIQFDTQVHSRNEPNGYDNWNSPTVPFSSVNSIGVPSGPIEREPYIPQIIDINYIEGSNDQKWSSRDFPWTRKLEANNKKVFGNHSFRPNQREVINATMSGYDVFVLMPTGGGKSLTYQLPALICPGITLVISPLVSLIQDQIMHLLQANIPAAYLSANMDWSEQQEILTELTSDYCKYKLLYVTPEKVAKSDVLLRHLNILNSRDLLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPKTPVLALTATATASVKEDVVQALGLINCIIFRQSFNRPNLWYSVIPKTKKCVEDIDKLIKENHFDECGIIYCLSRMDCEKVAEKLQEYGHKAAFYHGNMDPAQRAFIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCLLYYSYSDYIRVKHMISQGAAEQSPLITGHSRFNNSGRILETNTENLLRMVGYCENDVDCRRLLQLLHFGEKFNSTHCQKTCDNCCKTRSSVDKDVTNIAKQLVELIKLTGQQFSSSHILEVFRGSLSQFVKKHRHETLSLHGVGKHLAKGEASRIIHHLVVEEYLLEDVKKSDIYGSVSSVLKVNESKIP
Length983
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.427
Instability index45.64
Isoelectric point7.07
Molecular weight110652.28
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12872
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.77|      17|      42|     853|     869|       1
---------------------------------------------------------------------------
  853-  869 (30.45/19.15)	RRLLQLLHF.GEKFNSTH
  893-  910 (24.32/13.87)	KQLVELIKLtGQQFSSSH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.15|      37|      42|     372|     413|       2
---------------------------------------------------------------------------
  374-  413 (60.34/47.75)	QYGTPqTTSLRTNPiqFDTQVHSRNEPNGYDN..WNSPTVPF
  418-  456 (63.81/34.37)	SIGVP.SGPIEREP..YIPQIIDINYIEGSNDqkWSSRDFPW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.41|      36|      42|      59|      99|       3
---------------------------------------------------------------------------
   59-   99 (55.29/38.33)	RLTSRQIQNSQIFQHTQVEkawqiLSSLPASCRTYLKPGTS
  103-  138 (60.12/31.18)	KTSTDEISHNRRGRSTLVE.....LSGMKRSEHMHVHPNSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.69|      15|      42|     642|     656|       4
---------------------------------------------------------------------------
  642-  656 (25.34/15.63)	VKEDVVQALGLINCI
  686-  700 (29.35/19.26)	IKENHFDECGIIYCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.98|      14|      42|     141|     155|       5
---------------------------------------------------------------------------
  141-  155 (22.21/16.96)	ESKVNGfGRCMTSSF
  184-  197 (24.77/13.51)	NSKVSG.GSLKNQTF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.81|      23|      42|     307|     330|       7
---------------------------------------------------------------------------
  307-  330 (33.17/25.72)	VQEMKDMLIAV....SNELLDNATnLSL
  347-  373 (32.64/20.07)	IQQLEKYLSDVerqkSNFSASTAT.LSF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12872 with Med34 domain of Kingdom Viridiplantae
Unable to open file!