<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12871

Description ATP-dependent DNA helicase Q-like 4A isoform X2
SequenceMPDQNDSVESQKCYDKLPNVNWLRHFDAHDKFACQNKFLCTNFLFSLEGQKPQGTMFARLTSRQIQNSQIFQHTQVEKAWQILSSLPASCRTYLKPGTSAPVKTSTDEISHNRRGRSTLVELSGMKRSEHMHVHPNSSETESKVNGFGRCMTSSFPSNNANTMESGNNLRGNSGITTSMFSHSNSKVSGGSLKNQTFHGVQQEQSADVLANEIDDDDLLKDIDVDQIVSEHYQSTCTPQPSVSKFLPITPSVDKNAFAGQETCLPPELCSNCSHGCKLGHCPEAASHVQEMKDMLIAVSNELLDNATNLSLEQIEKLRQDRLQLNKLIQQLEKYLSDVERQKSNFSASTATLSFQYGTPQTTSLRTNPIQFDTQVHSRNEPNGYDNWNSPTVPFSSVNSIGVPSGPIEREPYIPQIIDINYIEGSNDQKWSSRDFPWTRKLEANNKKVFGNHSFRPNQREVINATMSGYDVFVLMPTGGGKSLTYQLPALICPGITLVISPLVSLIQDQIMHLLQANIPAAYLSANMDWSEQQEILTELTSDYCKYKLLYVTPEKVAKSDVLLRHLNILNSRDLLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPKTPVLALTATATASVKEDVVQALGLINCIIFRQSFNRPNLWYSVIPKTKKCVEDIDKLIKENHFDECGIIYCLSRMDCEKVAEKLQEYGHKAAFYHGNMDPAQRAFIQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCLLYYSYSDYIRVKHMISQGAAEQSPLITGHSRFNNSGRILETNTENLLRMVGYCENDVDCRRLLQLLHFGEKFNSTHCQKTCDNCCKTRSSVDKDVTNIAKQLVELIKLTGQQFSSSHILEVFRGSLSQFVKKHRHETLSLHGVGKHLAKGEASRIIHHLVVEEYLLEDVKKSDIYGSVSSVLKVNESKVKNLFSGSQAIIIRFPSTVKVGKLSKPEVTPAKGSLTTSGKLSPPIVDTPAQSQSIVDLNLSAKLYSALRMLRTILVKEAGEGVMAYHIFGNATLQHISKRVPRTKEELLEINGIGKAKILKYGDRLLETIEATIKEHYKADKISSGSSNDSNDSAKRRRNTNANIDNDDDFSRSTGRSKKRTVERQDKDGNSDNNHQYPADENDLDFDDLDYVYDVESKENRPQVEVNINGRVLPSWPRT
Length1203
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.07
Grand average of hydropathy-0.520
Instability index46.46
Isoelectric point7.55
Molecular weight135158.11
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12871
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.34|      24|     134|     432|     457|       1
---------------------------------------------------------------------------
  432-  457 (37.92/35.64)	SRDFpWTRKL..EANNKKVFGnHSFRPN
  571-  596 (42.42/28.14)	SRDL.LARIVidEAHCVSQWG.HDFRPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.93|      41|     134|     893|     967|       2
---------------------------------------------------------------------------
  734-  785 (59.45/25.09)	GMGINKPDVRFVIHHSLpksIEGYHQEcgragrDGQRSSclLYYSYSDYIRV
  918-  958 (68.48/ 9.19)	GKHLAKGEASRIIHHLV...VEEYLLE......DVKKSD..IYGSVSSVLKV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     212.42|      67|     706|     130|     200|       3
---------------------------------------------------------------------------
  130-  200 (109.68/90.93)	HMHVHPNSSETESKVNGFgrCMTSSfpSNNANTMESGNNLRGNSGITTSMFSHSN.SKVSGGSL.......KNQT..FHGV
  841-  917 (102.75/71.08)	HFGEKFNSTHCQKTCDNC..CKTRS..SVDKDVTNIAKQLVELIKLTGQQFSSSHiLEVFRGSLsqfvkkhRHETlsLHGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     208.01|      63|     123|     237|     301|       5
---------------------------------------------------------------------------
  237-  301 (110.11/61.18)	TPQPSVSKFLPI...TPSVDKNAFAGQETCLPP..ELCSNCSHGCKLGhcP.EAASHVQEMKDM.LIAVSNE
  358-  427 (97.90/48.45)	TPQTTSLRTNPIqfdTQVHSRNEPNGYDNWNSPtvPFSSVNSIGVPSG..PiEREPYIPQIIDInYIEGSND
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12871 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) APVKTSTDEISHNRRGRSTLVELSGMKRSEHMHVHPNSSETESKVNGFGRCMTSSFPSNNANTMESGNNLRGNSGITTSMFSHSNSKVSGGSLKNQTFHGVQQEQSADVLANEI
2) DLDYVYDVESKENRPQVEVNINGRVLPSWPRT
3) YKADKISSGSSNDSNDSAKRRRNTNANIDNDDDFSRSTGRSKKRTVERQDKDGNSDNNHQYPADENDLD
100
1172
1101
213
1203
1169










Molecular Recognition Features






MoRF SequenceStartStop




NANANA