<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12870

Description luminal-binding protein 5-like
SequenceMVAKNKALWVLFLFMSEFLLGIAVASNDSKVGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDSERLIGEAAKNQAALNAERTIFDVKRLIGRKFNDPEVQRDIKFLPYKVVNKDGKPYIQVKVKGETKVFSPEEISAMVLTKMKETAEAYLGKKIKDAVITVPAYFNDAQRQATKDAGTIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVYDLGGGTFDVSILTIDNGVFEVLSTSGDTHLGGEDFDHRVMDYFIKLIKKKYNKDISKDNKALGKLRRECERAKRALSSQHQVRVEIESLFDGVDFSEPLTRARFEELNMDLFKKTLGPVKKALEDANLKTSDINEIVLVGGSTRIPKVQQLLKDLFDGKEPNKGINPDEAVAYGAAVQGGILSGEGGEETKDILLLDVAPLSLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQSTVSIKVYEGERSLTKDCRELGRFDLTGIPPAPRGVPQIEVTFEVDANGILHVTAEDKAAKKAQSITITNDKGRLSQEEIDRMAKEAEEFAEEDKKVREKIDSRNKLETYIYNMRSSIDDKDKLADKIDSDEKEKIENTLREALEWLDDNQNGEKEDFDEKLKEVEAVRNPIIKQVYEKSGGSSANDDEPTDEL
Length656
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.458
Instability index31.96
Isoelectric point5.22
Molecular weight72744.65
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12870
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.80|      25|      26|     558|     582|       1
---------------------------------------------------------------------------
  558-  579 (30.13/15.75)	.....KVREKIDS..RNKLETYIYNMRSS
  580-  608 (28.65/14.63)	IDDkdKLADKIDSdeKEKIENTLREALEW
  609-  633 (32.02/17.18)	LDD.nQNGEKEDF..DEKLKE.VEAVRNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.93|      18|      59|       9|      28|       2
---------------------------------------------------------------------------
    9-   28 (25.11/26.20)	WVLFLfMSEFLLGIAvASND
   69-   86 (33.82/22.76)	WVAFT.DSERLIGEA.AKNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.10|      17|      17|     179|     195|       4
---------------------------------------------------------------------------
  168-  186 (19.32/ 9.97)	KDAvITVpAYFNDAQRQAT
  187-  203 (28.78/18.05)	KDA.GTI.AGLNVARIINE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.76|      23|      27|     501|     526|       8
---------------------------------------------------------------------------
  501-  526 (28.28/28.94)	IEVTfeVDaNGILHVTAEDKAAKKAQ
  528-  550 (38.48/25.17)	ITIT..ND.KGRLSQEEIDRMAKEAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.32|      13|      27|     103|     119|       9
---------------------------------------------------------------------------
  103-  119 (19.38/18.96)	GRkfndPEVQRDIK.....FLP
  127-  144 (18.94/ 8.30)	GK....PYIQVKVKgetkvFSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.06|      13|     186|     208|     223|      10
---------------------------------------------------------------------------
  208-  223 (19.13/18.30)	AIAYGLDKKGGeknIL
  395-  407 (23.93/13.52)	AVAYGAAVQGG...IL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12870 with Med37 domain of Kingdom Viridiplantae
Unable to open file!