<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12863

Description heat shock cognate 70 kDa protein
SequenceMAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVGFTDTERLIGDAAKNQVAMNPLNTVFDAKRLIGRRFSDAAVQSDIKLWPFKVIPGSGDKPMIVVSYKGEEKQFAAEEISSMVLIKMREIAEAYLGFTVKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGNPRALRRLRTSCERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKSSVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERARTRDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKEEIEKMVQEAEKYKSEDEEHKKKVDAKNALENYAYNMRNTVKDEKIGAKLAAADKKKIEDAIDEAIQWLDNNQLAEADEFEDKMKELESICNPIIAKMYQGAGADMGGMDEDAPASGTGAGPKIEEVD
Length646
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.06
Grand average of hydropathy-0.389
Instability index31.96
Isoelectric point5.11
Molecular weight70868.56
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12863
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.56|      20|      41|     337|     356|       1
---------------------------------------------------------------------------
  337-  356 (33.75/21.38)	VHDVVLVGGSTRIP.KVQQLL
  381-  398 (26.48/15.29)	VQAAILSGEGNE...KVQDLL
  414-  434 (27.33/16.00)	GVMTVLIPRNTTIPtKKEQVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.73|      55|     259|     178|     238|       2
---------------------------------------------------------------------------
  178-  238 (77.38/61.29)	NEPTAAAIAYGLDKKATSvgEKNVL.IFDLGG...GTFDVSLLTIeegIFEVKATaGDTHLGGED
  440-  498 (85.35/49.91)	NQPGVLIQVYEGERARTR..DNNLLgKFELSGippAPRGVPQITV...CFDIDAN.GILNVSAED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.87|      16|      21|      13|      32|       3
---------------------------------------------------------------------------
   13-   28 (33.50/31.77)	DLG..TTYSCVGVWQHDR
   35-   52 (26.37/12.88)	DQGnrTTPSYVGFTDTER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.86|      32|     398|     102|     171|       4
---------------------------------------------------------------------------
   54-   90 (44.25/65.37)	IGDAAKNQVAMNPlnTVF.DAKRLIGRrfsDAAVQSDI
  139-  171 (49.61/19.75)	LGFTVKNAVVTVP..AYFnDSQRQATK...DAGVIAGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.06|      35|      42|     528|     568|       5
---------------------------------------------------------------------------
  528-  564 (49.21/43.29)	AEKYKSED..EEHKKKVDaKNALENyAYNMRNTVKD.EKI
  571-  608 (48.85/25.31)	ADKKKIEDaiDEAIQWLD.NNQLAE.ADEFEDKMKElESI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.30|      24|     397|     102|     127|       6
---------------------------------------------------------------------------
  102-  127 (35.53/28.59)	GDKPMIVVSykGEEKQFAAEEISSMV
  502-  525 (39.76/24.82)	GQKNKITIT..NDKGRLSKEEIEKMV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12863 with Med37 domain of Kingdom Viridiplantae
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