<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12862

Description mediator of RNA polymerase II transcription subunit 25-like isoform X3
SequenceMFPIAANGNQTHQIADGQRHCILVAASNPYPLPTPVYRPQTQNLEQSENMESQTESRLSDAETVAKSFPQCSVSLSVICPKQLSKLKAIYSAGNRNPRASDPPVDNVRNPQFLVLISENFMEGCAALSRSGVPSLAPNQSPVKMDMASVTSVAGTSPTSVPSVNGSIMSRQPVSVGNVPTATVKVEPATITSMANGPAFPHIPSVPRAPFQAVPTLQTSSPLTTTEEVMRSSDNVQEIKPSVGGMTQPLRPVPPAAANVNILNNLSQARVMNSAALSGGTSIGLQSMGQTPVAMHMSNMISSGMTSSVPLAQTVFSSGQSAMTSLPGSGAVTGTTQVPPNSNLNSFASATSNVAGNSNIGISQPMCNVQGAVSMGQSVPGSMSQGNHSGAQLVQTGVAMSQSMSGLGPSTVSSGTGTLIPTPGLSQQVQSGMQTIGVNNNSAASMPLSQQTSSALQSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASETLASDWPQTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLGQLQEKKLCAVIQLPSQTLMLSVSDKAYRLIGMLFPGDMVVFKPQISSQHQQQQQQMQPLLQQQQMPQQQQQQQQQLPQLQQQQQLPQLQQQQQQQPQQQQPLPHLQQQQLPQLQQQQQQQQQLSQMQQQQMPQLQQQPQLAQMPQQQQQMVGSGINSAYVQGPGRSQLVSQGQVSSQAPSNMPGGGFMS
Length728
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.03
Grand average of hydropathy-0.413
Instability index70.83
Isoelectric point9.22
Molecular weight77758.91
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12862
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     174.40|      24|      24|     606|     629|       1
---------------------------------------------------------------------------
  594-  613 (36.42/ 9.34)	QMQPLLQQQQMPQ..........qQQQQQQ
  614-  639 (48.25/14.87)	QLPQLQQQQQLPQLQQ...qqQQ.QPQQQQ
  640-  660 (46.43/14.02)	PLPHLQQQQ.LPQL.......QQ.QQQQQQ
  661-  688 (43.30/12.55)	QLSQM.QQQQMPQLQQqpqlaQM.PQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.75|      24|      24|     261|     284|       2
---------------------------------------------------------------------------
  261-  284 (40.11/18.19)	ILNNLSQ........ARVMNSAA....LSGGTSIGL
  420-  455 (22.64/ 6.71)	PTPGLSQqvqsgmqtIGVNNNSAasmpLSQQTSSAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.77|      19|      24|     368|     389|       3
---------------------------------------------------------------------------
  311-  333 (26.42/ 8.23)	AQTVFSSGQsamtSLPGS...GAVTG
  368-  389 (31.35/17.17)	VQGAVSMGQ....SVPGSmsqGNHSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.44|      10|      15|     334|     343|       4
---------------------------------------------------------------------------
  334-  343 (19.32/10.35)	TTQVPPNSNL
  350-  359 (17.12/ 8.21)	TSNVAGNSNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     159.88|      37|      40|     127|     163|       5
---------------------------------------------------------------------------
  127-  156 (44.18/17.49)	............LSRSGV..............................PSLAPNQSPVKMDMASVT...........SVA.G.TS
  157-  198 (48.08/19.70)	P.TSVPSVngsiMSRQPV..............................SVGNVPTATVKVEPATIT...........SMAnG.PA
  199-  247 (38.61/14.34)	F.PHIPSV..prAPFQAV..............................PTL.QTSSPLTTTE.EVMrssdnvqeikpSVG.GmTQ
  248-  306 (29.00/ 8.91)	PlRPVPP...........aaanvnilnnlsqarvmnsaalsggtsiglQSMG..QTPVAMHMSNMI...........SSG.M.TS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.61|      23|      69|      26|      51|       6
---------------------------------------------------------------------------
   26-   51 (32.15/27.44)	ASNPyPLPTpVYRPQTQNLeQSEN.ME
   99-  122 (39.46/19.09)	ASDP.PVDN.VRNPQFLVL.ISENfME
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.14|      24|     127|     563|     587|      10
---------------------------------------------------------------------------
  517-  542 (26.57/15.10)	NKQY..VG...KADFLVFRamnqhgflGQL..Q
  543-  555 (22.92/11.83)	EK..KLCAVI..................QLPSQ
  563-  587 (39.66/32.91)	DKAYRLIGMLfPGDMVVFK........PQISSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.45|      12|     429|      59|      70|      11
---------------------------------------------------------------------------
   59-   70 (21.55/12.16)	SDAETVAKSFPQ
  491-  502 (22.90/13.34)	SASETLASDWPQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12862 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KVEPATITSMANGPAFPHIPSVPRAPFQAVPTLQTSSPLTTTEEVMRSSDNVQEIKPSVGGMTQPLRPVPPAAAN
2) MSGLGPSTVSSGTGTLIPTPGLSQQVQSGMQTIGVNNNSAASMPLSQQ
3) QQLSQMQQQQMPQLQQQPQLAQMPQQQQQMVGSGINSAYVQGPGRSQLVSQGQVSSQAPSNMPGGGFMS
4) SGVPSLAPNQSPVKMDMASVTSVAGTSPTSVPSVNGSIMSRQPVSVGNVPTAT
5) TPVYRPQTQNLEQSENMESQTESRLSDAET
184
403
660
130
34
258
450
728
182
63










Molecular Recognition Features






MoRF SequenceStartStop




NANANA