<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12861

Description mediator of RNA polymerase II transcription subunit 25-like isoform X2
SequenceMAEKQLIVAVEGTAAMGPYWQIILSDYLEKIIRCFCSNEFAGQKNTTSNVELSLVAFNTHGSYCACLVQRSGWTKDVDIFLQWLSAIPFSGGGFNDAAIAEGLSEALMMFPIAANGNQTHQIADGQRHCILVAASNPYPLPTPVYRPQTQNLEQSENMESQTESRLSDAETVAKSFPQCSVSLSVICPKQLSKLKAIYSAGNRNPRASDPPVDNVRNPQFLVLISENFMEGCAALSRSGVPSLAPNQSPVKMDMASVTSVAGTSPTSVPSVNGSIMSRQPVSVGNVPTATVKVEPATITSMANGPAFPHIPSVPRAPFQAVPTLQTSSPLTTTEEVMRSSDNVQEIKPSVGGMTQPLRPVPPAAANVNILNNLSQARVMNSAALSGGTSIGLQSMGQTPVAMHMSNMISSGMTSSVPLAQTVFSSGQSAMTSLPGSGAVTGTTQVPPNSNLNSFASATSNVAGNSNIGISQPMCNVQGAVSMGQSVPGSMSQGNHSGAQLVQTGVAMSQSMSGLGPSTVSSGTGTLIPTPGLSQQVQSGMQTIGVNNNSAASMPLSQQTSSALQSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASETLASDWPQTMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLGQLQEKKLCAVIQLPSQTLMLSVSDKAYRLIGMLFPGDMVVFKPQISSQHQQQQQQMQPLLQQQQMPQQQQQQQQQLPQLQQQQQLPQLQQQQQQQPQQQQPLPHLQQQQLPQLQQQQQQQQQLSQMQQQQMPQLQQQPQLAQMPQQQQQMVGSGINSAYVQGPGRSQLVSQGQVSSQAPSNMPGGGFMS
Length836
PositionUnknown
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.04
Grand average of hydropathy-0.326
Instability index65.17
Isoelectric point8.27
Molecular weight89515.24
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12861
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     174.40|      24|      24|     714|     737|       1
---------------------------------------------------------------------------
  702-  721 (36.42/ 8.28)	QMQPLLQQQQMPQ..........qQQQQQQ
  722-  747 (48.25/13.07)	QLPQLQQQQQLPQLQQ...qqQQ.QPQQQQ
  748-  768 (46.43/12.33)	PLPHLQQQQ.LPQL.......QQ.QQQQQQ
  769-  796 (43.30/11.06)	QLSQM.QQQQMPQLQQqpqlaQM.PQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.75|      24|      24|     369|     392|       2
---------------------------------------------------------------------------
  369-  392 (40.11/18.56)	ILNNLSQ........ARVMNSAA....LSGGTSIGL
  528-  563 (22.64/ 7.00)	PTPGLSQqvqsgmqtIGVNNNSAasmpLSQQTSSAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.77|      19|      24|     476|     497|       3
---------------------------------------------------------------------------
  419-  441 (26.42/ 9.64)	AQTVFSSGQsamtSLPGS...GAVTG
  476-  497 (31.35/19.94)	VQGAVSMGQ....SVPGSmsqGNHSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.44|      10|      15|     442|     451|       4
---------------------------------------------------------------------------
  442-  451 (19.32/ 9.78)	TTQVPPNSNL
  458-  467 (17.12/ 7.79)	TSNVAGNSNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.08|      27|      29|     265|     291|       5
---------------------------------------------------------------------------
  246-  271 (30.25/12.65)	NQS.....PVKMDMASVTSV...agtsP.TSVPSV
  272-  301 (39.95/19.24)	NGSIMSRQPVSVGNVPTATV....kveP.ATITSM
  303-  336 (31.88/13.76)	NGPAFPHIP.SVPRAPFQAVptlqtssPlTTTEEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.52|      10|      29|      52|      61|       6
---------------------------------------------------------------------------
   52-   61 (17.91/10.14)	LSLVAFNTHG
   84-   93 (18.61/10.81)	LSAIPFSGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.61|      23|      70|     134|     159|       8
---------------------------------------------------------------------------
  134-  159 (32.15/33.43)	ASNPyPLPTpVYRPQTQNLeQSEN.ME
  207-  230 (39.46/23.31)	ASDP.PVDN.VRNPQFLVL.ISENfME
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.36|      14|     127|     682|     695|      10
---------------------------------------------------------------------------
  682-  695 (27.17/14.90)	PG.DMVVFKPQISSQ
  810-  824 (21.19/ 9.77)	PGrSQLVSQGQVSSQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12861 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KVEPATITSMANGPAFPHIPSVPRAPFQAVPTLQTSSPLTTTEEVMRSSDNVQEIKPSVGGMTQPLRPVPPAAAN
2) MSGLGPSTVSSGTGTLIPTPGLSQQVQSGMQTIGVNNNSAASMPLSQQ
3) QQLSQMQQQQMPQLQQQPQLAQMPQQQQQMVGSGINSAYVQGPGRSQLVSQGQVSSQAPSNMPGGGFMS
4) SGVPSLAPNQSPVKMDMASVTSVAGTSPTSVPSVNGSIMSRQPVSVGNVPTAT
292
511
768
238
366
558
836
290










Molecular Recognition Features






MoRF SequenceStartStop




NANANA