<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12857

Description mediator of RNA polymerase II transcription subunit 23-like isoform X2
SequenceMDQTQRSVAAAANSRTYQFHPARAAITDLFNLYLGRNSRQKADDSVREPPNKTQKRVLALNRELPPRNEQFLLDFEQLQTQFGDQDQLQSVTESVLISLVIQCCSHAPRAEFLLFALRSLCSIGYVNWDTFLPSLLSSVASAEGPVSQGSQGVPSVSSSVSQSGMMPSTSVIANASNFQSANAASTLTSVHVIGSPAQSTIEPSSGATLSPVKLSNIACSGQPSTTRMDSSIRDNAISNLRQLCCKIILTGLECNLKPVTQAEIFHHMLNWLVNWDQRQHGNEECDGKSWRLEKALIEWLHSCLDVIWLLVEEDKCRVPFYELLRSGLQFIENIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHCPTFGTHRILSQTTPNVSVEGVANLRYSPITYPSVLGEPLHGEDLAASIQRGSLDWERALRCIRHAIRSTPSPDWWKRVLVVAPFYRGSVPTPGAVFTCDMICEATIDRIVELLKLTNSEINCWQEWLVFSDIFFFLMKSGCIDFVDFIDKLGSRLSASDHHILNTNHVTWLLAQIIRVEHVMTALNTDSRKVETTRKILSFHREDRSSDPNNPQSILLDFISSCQNLRIWSLNTSTREYLNNEQLQKGKQIDEWWRQVSKGERMMDYMSMDDKSIGMFWVVSYTMAQPACETVMNWLSSGGVTELLPGANVQPNERFMVMREVSPLPISLLSGFSMNLYLKLVFQMEESLFAGQVVPSIAMVETYTRLLLIAPHSLFRSHFSHLAQRNASLLSKPAVTLLVLEIVNYRLLPLYRYQGKCKPLMYDVTKIISALKGKRGDHRVFRLAENLCINLILSLRDFFSVKREGKGPTEFTETLNRITIITLAITIKTRGIADADHLLYLQTMLEQILATSQHTWSEKTLRFFPSILRDLLMTRTDKRGLAIQEWLQSETTVINQCTQLLSSSAEPNYVMTYINHSFPQHRQYLCAGAWILMQGHPENINSGNLARVLREFSPEDVTSNIYTMVDVLLHHIHIELQHGHSLQDLLLKTCANLAFFVWTHELIPLDILLLALIDRDDDPHALRIVISLLDRQELQQRVKLYCMNRGPPEHWLYTGIFKRSDLQKALGNHLSWKERYPTFFDDIVARLLPVIPLVVYRLIENDAIESADRILGMYSLFLAYHPLRFTFVRDILAYFYGHLPGKLIVRILNVLDLSKIPFSESFPQHISSSNPAICPPLEYFATLLLALVNNVIPPLNSNSRTGSMGDASNNSVRGPHNKTPATPQSGPANASEGQKAFYQIQDPGTYTQLVLETAVIEILSLPISASQIVSSLVQIVVNIQPTLIQSSNGLHGASSGAVQGSVLPTSPSGGSTDSAGRSTPSVSGINTSSFVSRSGYTCQQLSCLFIQACGLLLAQLPPEFHLQLYMEASRIIKESWWLTDGKRSLSELDSAVSYALLDPTWASQDNTSTAIGNIVALLHSFFSNLPQEWLEGTHVIIQQLRPVTSVAMLRIAFRIMGPLLPRLVTAHNLFNKILSLLLNTLVDVFGKNTQPPVPVEASEITDLIDYLHHIIHYEGQAGPVQANSKPRPEVLSICGRAAESLRPDVQHLLSHLKPDVNSSIYAATHPKIAQNPSS
Length1603
PositionTail
OrganismGossypium hirsutum (Upland cotton) (Gossypium mexicanum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Malvales> Malvaceae> Malvoideae> Gossypium.
Aromaticity0.08
Grand average of hydropathy-0.054
Instability index48.91
Isoelectric point6.45
Molecular weight179868.46
Publications
PubMed=25893780

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12857
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.20|      14|      15|     958|     971|       1
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  958-  971 (27.39/17.44)	AWILMQGHPENINS
  975-  988 (23.80/14.14)	ARVLREFSPEDVTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.39|      15|      15|    1191|    1205|       2
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 1191- 1205 (29.20/15.02)	FPQHISSSNPAICPP
 1209- 1223 (24.19/11.24)	FATLLLALVNNVIPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.92|      17|      17|     421|     437|       4
---------------------------------------------------------------------------
  421-  437 (32.23/18.09)	DWERALRCIRHAIR.STP
  440-  457 (28.69/15.34)	DWWKRVLVVAPFYRgSVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.94|      20|     540|     989|    1008|       5
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  989- 1008 (38.05/22.20)	NIYTMVDVLLHHIHIELQHG
 1528- 1547 (37.88/22.07)	EITDLIDYLHHIIHYEGQAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.76|      12|      15|    1034|    1046|       6
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 1034- 1046 (15.25/12.52)	LDIlLLALIDRDD
 1051- 1062 (19.51/10.96)	LRI.VISLLDRQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.27|      21|     540|     913|     934|       7
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  913-  934 (33.78/27.62)	QEWLQSeTTVINQCTQLLSSSA
 1456- 1476 (38.50/26.44)	QEWLEG.THVIIQQLRPVTSVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     236.74|      83|     544|      56|     180|       8
---------------------------------------------------------------------------
   75-  164 (119.56/119.58)	FEQLQTQfGDQDQL...........QSVTESVLISLVIQCCSH.APRaefLLFALRSL..CSIGYVNwDTFLPSLLS..SVASAeGPVSQGSQGVpSVSSSVSQSG
 1266- 1364 (117.18/75.41)	FYQIQDP.GTYTQLvletavieilsLPISASQIVSSLVQIVVNiQPT...LIQSSNGLhgASSGAVQ.GSVLPTSPSggSTDSA.GRSTPSVSGI.NTSSFVSRSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.48|      19|      20|     169|     187|       9
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  169-  187 (31.09/18.52)	TSVIANASNFQSA...NAASTL
  188-  209 (27.38/15.45)	TSVHVIGSPAQSTiepSSGATL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.30|      17|      20|    1225|    1243|      10
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 1225- 1243 (25.33/24.28)	NSNSRTGSMGDAsnNSVRG
 1246- 1262 (30.97/21.60)	NKTPATPQSGPA..NASEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.12|      17|     221|     885|     901|      11
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  885-  901 (31.50/22.83)	WSEKTLRFFPSILRDLL
 1101- 1117 (32.63/23.96)	WKERYPTFFDDIVARLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.76|      22|     181|     308|     334|      14
---------------------------------------------------------------------------
  308-  334 (34.39/34.97)	WLLVEEdkcrvPFYELLRSG.LQFIENI
  493-  515 (37.37/23.84)	WLVFSD.....IFFFLMKSGcIDFVDFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.45|      16|      23|     703|     718|      17
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  703-  718 (28.31/17.93)	M.NLYLKLVFQMEESLF
  728-  744 (24.14/14.16)	MvETYTRLLLIAPHSLF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.83|      22|      23|     654|     675|      21
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  629-  650 (21.13/ 7.49)	....E.RMMDYMSmddkSIGMFWVVSY
  654-  675 (40.46/20.35)	QPACE.TVMNWLS....SGGVTELLPG
  679-  700 (31.24/14.22)	QPNERfMVMREVS....PLPIS.LLSG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12857 with Med23 domain of Kingdom Viridiplantae
Unable to open file!