<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12781

Description mediator of RNA polymerase II transcription subunit 33A-like
SequenceMVAESTRFEDRVLETVKCCQERKDPPLVWAMEVSKCVREAGFSLPSPELGVVLVSSLCFSNNNPYLWKFLDQAISSGLLSSLQVLALLTSRVIPHRRTQPEAYRLYLELLSRYALFLAPVGTNPCREKIVISVDDALELSKNYGFHVVEFGQAVVLFLFTVIINLIDSTMDDWGLQPASVGKISGLFGGGEHQDMDIDSKGNQNDKRREHCELLKKTNAFMTMEVLGKLTENRKVMVLLRLVHLNMAEKFNGLLQRIQFLESHKSVSPNIKSSSQILVRLSANIKRGLDLEYQLNKRQLFGVMIDIGSCSSASSYNFGAGRAACWVPFDIYVETAMDGRQLPATSAVDVLTDLTKTLQVINRASWQETFQALWVSALRLVQRERDPLEGPIPHLDARFCVLLCVVPLAIVHVLEDEREGTSSGNMGTNCNHGMGGTDYASRRQGLVACLKVLGQFSGLLSPPLSIASAANSAASKAANFISNFRNGNDGFSGSGHGDNCVKAGGNMLHLIVEACIARKLIDTSAYFWPGYVSTSSTSLSDSSPVQVSPWSAFMDGANLAGPLRNALIATPASSLAEIEKLYHIAINGSEEERSAAAKILCGASLSRGWNIQEHVVHFVVRLLSPPIPPNFSGPGSHLIDYMSMLNAILFGVSSSDTIHILSLHGLVPEVAASLMPLCEAFGSLVPTSCQKSSTGDEISAYTTFSCAFLLLLRLWKFYRPPHEHCITEHGGTTGSELTLEYLLLLRNSRIAPHNSKPLDNTKKVSNLPEPSSAYPIYIDFYPKLRSWYCQNKACIASTLSGLCSGSPVHQIANKVLSMICRKMTKGGTVSGNASTPSSNSASGSPVSAGEDAYQRPMLPAWDILEATPFVLEAVLTACAHGRLSSRDLTTGLSDLVDFLPASLAAIVTYFSAEITRGIWKLVSMNGIEWPSPAANLLSIESEIKEILAAAGINAPNCYTEGPPVMLPLPMAAMLSLTLTFKLDKNLEYIHTVAGSALDNCASSCPWPSMPIIGALWAQKARRWHDFIVVSCSRSAFKQDQAAVAQLLRSCFTSFLGSPHVTVSPMTAQRGVNGLLGSKISACGIRPSIAPGFLYLRTCRTIHNVQFVNDVILGLVSKSAQESAARWACANSTRLKSSRVSLASATSWAKEVATLGASLLCVAGGVQLVQVLYKETIPTWLLSTREEKPTGVGPVSRILEGYAVAYLVFLSGSFVWGVGATSSTRAHSRRARIVGVHVDFVAGALEGNISLGCDPTTWKAYVSCFVGLVVHFAPAWIQEVRQEILRKLANGLRGWHECELALALLERGGIATMGYVAELIHGIC
Length1322
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.08
Grand average of hydropathy0.132
Instability index43.63
Isoelectric point8.03
Molecular weight143287.51
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12781
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     139.89|      43|      76|     324|     372|       1
---------------------------------------------------------------------------
  324-  372 (61.39/63.42)	CWVPFDIyVETAMDGRQlpATSAVDVLTDLTKTLQVINRASWQetfQAL
  403-  445 (78.50/55.55)	CVVPLAI.VHVLEDERE..GTSSGNMGTNCNHGMGGTDYASRR...QGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     150.62|      38|      76|     749|     786|       2
---------------------------------------------------------------------------
  691-  714 (24.95/11.26)	...............SSTGDEISAYTTFsCAFLLLLRLW
  749-  786 (69.00/45.52)	IAPHNSKPLDNTKKVSNLPEPSSAYPIY.IDFYPKLRSW
  828-  860 (56.67/35.93)	VSGNASTPSSNSASGSPVSAGEDAYQ......RPMLPAW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     217.26|      69|     684|     525|     608|       4
---------------------------------------------------------------------------
  528-  604 (105.43/97.61)	PGYVSTSSTSLSDSSPVQVS.PWSAFMDGANLAgplrNALIATPASSlaeiEKLYHIAINGSEEERSAAAKILCGA..SL
  612-  683 (111.83/63.31)	EHVVHFVVRLLSPPIPPNFSgPGSHLIDYMSML....NAILFGVSSS....DTIHILSLHGLVPEVAASLMPLCEAfgSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     362.93|     120|    1095|      10|     138|       6
---------------------------------------------------------------------------
   10-  138 (191.08/120.07)	DRVLETV.KCCQErkdPPLVWAMEVSKCVREAGFSLPSP.....ELGVVLVSSLCFSNNNPYLWKFLDQAISSGLLSSLQVLAlltSRVIPHRRTQpEAYRL.YLELLSryALFLAPVGTNPC......REKIV.ISVD...DALE
 1108- 1244 (171.85/88.80)	DVILGLVsKSAQE...SAARWACANSTRLKSSRVSLASAtswakEVATLGASLLCVAGGVQLVQVLYKETIPTWLLSTREEKP...TGVGPVSRIL.EGYAVaYLVFLS..GSFVWGVGATSStrahsrRARIVgVHVDfvaGALE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.45|      25|     514|     209|     233|       8
---------------------------------------------------------------------------
  209-  233 (44.46/27.16)	EHC..ELLKKTNAFMTMEVLGKLTENR
  722-  748 (39.99/23.76)	EHCitEHGGTTGSELTLEYLLLLRNSR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12781 with Med33 domain of Kingdom Viridiplantae
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