<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP12780

Description mediator of RNA polymerase II transcription subunit 33A isoform X2
SequenceMTTSVHTTLWDSVIELTKGAQDKGTDPLLWAIQLSSSLNSAGVSLPSTEVAHLLVSHICWGNNVPITWKFLEKTLIVKIAPPILVLALLSCRIMKSIDDVLHLSHIFGLQACESGVLVVEFFFAIVWQLLDATLDDEGLLELTPEKESKWAIRPQDMEVDVHDSFGERRTEHKDRLHKANTVMAIELIGQFLQNKATSKILYLARRNMPLHWGSFTQRLQLLGANSSALRSSKISSDALLQLSSDTCKIFSRGCRMSTQQEFHAVMASGSMTFSAGQCYWASQSSVWLPLDLFLEDSMDGSQVAATSAIETLSGLVKSLRAVNCATWHNAFLGLWIAALRHVQRERDPIEGPVSRLDTRLCLLLSITTLAIADIIEEEETALINEAGQSPNNQRKEKQVAGKRRRDLVSSLQILGDYEGLLTPPQSVISVANQAAMKAMMFVSGATVGSGYFECISKSDMPMSCFGNMWHLIVEACIARDLLDTSAYFWPGYVNRCINQVPHTVPGQAPGWSSLMKGTPLTPSMINVLVSSPASCLAELEKIFGVAVNGSDDEKISAATILCGASLIRGWNIQEHTIHFVIRLLSPPVPADYSGSDSHLIGYAPMLNTLLVGIASFDCIQVISLHGLVPQLAGALMPICEVFGSCVPHLSWSLTTGEEISSHAVFSNAFTLLLRLWRFNHPPLEQTVGDMPPVGSQLTPEYLLLVRNSQLVYSGNTSKDRNKSRRFSAATSPSSVQPIFVDSFPKLKLWYRQNQACIASTLSGVVHETPVHQIVDGLLNMMFRKMNKGNQSLTPGTSGSSSSSGPGNDEAPARPKLPAWDILEAIPFVLDAALTTCSHGRLSPRDLAIGLRDLSDFLPASLATIVSYFSAEVTRGIWKPAFMNGTDWPSPAANLSNIEEQIKRILAATGVDVPSLAAGGSSVATLPLPLAAFLSFTITFKLDRASERFLNLVGPALESLAVSCPWPCMPIVASLWAQKVKKWSDFLVFSASRTVFHHNSDAVVQLLKTCFTATLGLNSSPLSSNGGVGALLGHGFGSHFYGGFSPVAPGILYLRVHRSIRDIMFMTEEILSLLMFYVREIASDGKLRERTEKLNKSKYGMRYGQISLAAAMTRVKVAALLGASLVWLSGGLGLVQSLIKETLPSWFLSAHGSEQEGEGSEGIVAMLRGYALAYFAVICGAFAWGVDSTTSSSKRRPKILQAHMEFLASALDGKFSLGCDWATWQAYVSAFVNLMVECTPVWVLEVEVDVLKRLSKGLRQWNEEELALALLGSGGVEAMGAAAELVVESEI
Length1290
PositionTail
OrganismNelumbo nucifera (Sacred lotus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Proteales> Nelumbonaceae> Nelumbo.
Aromaticity0.08
Grand average of hydropathy0.160
Instability index47.40
Isoelectric point6.20
Molecular weight140394.27
Publications
PubMed=23663246

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP12780
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.04|      49|     160|     951|    1007|       1
---------------------------------------------------------------------------
  951- 1007 (65.55/73.60)	LVGPALESLAVScpwpcMPIVASLWAQKVKKWsdFLVFSASRTvFHHNSDAVVQLLK
 1119- 1167 (81.49/56.43)	LLGASLVWLSGG.....LGLVQSLIKETLPSW..FLSAHGSEQ.EGEGSEGIVAMLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.73|      42|     160|      91|     138|       2
---------------------------------------------------------------------------
   91-  138 (66.11/60.17)	CRImkSIDDVLHLSHIFGLQACESGvlvvEFFFA...IVWQLLDATLDD..EG
  254-  300 (70.62/47.66)	CRM..STQQEFHAVMASGSMTFSAG....QCYWAsqsSVWLPLDLFLEDsmDG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.77|      36|     166|    1009|    1044|       8
---------------------------------------------------------------------------
 1009- 1044 (66.29/42.48)	CFTATLGLNSSPLSSNGGVGALLGHG..FGSHFYGGFS
 1178- 1215 (59.47/37.27)	CGAFAWGVDSTTSSSKRRPKILQAHMefLASALDGKFS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP12780 with Med33 domain of Kingdom Viridiplantae
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